(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling - Wikidata - awgldk - TriplyDB

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling

http://www.wikidata.org/entity/Q28248215

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Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).Dopamine D1-Like Receptor Agonist and D2-Like Receptor Antagonist (-)-Stepholidine Reduces Reinstatement of Drug-Seeking Behavior for 3,4-Methylenedioxypyrovalerone (MDPV) in Rats.Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.

P2860

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P2860

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling

http://www.wikidata.org/entity/Q28248215

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2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

@zh-hk

2015年論文

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2015年論文

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2015年论文

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name

(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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type

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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prefLabel

(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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Psychopharmacology

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(-)-Stepholidine is a potent p ...... β-arrestin-mediated signaling

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Amy E Moritz

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David R Sibley

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Jennie L Conroy

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Julie A Meade

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Lani S Chun

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Nicole R Miller

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R Benjamin Free

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Trevor B Doyle

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Val J Watts

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P2860

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor

Dopamine receptors: from structure to function

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

The physiology, signaling, and pharmacology of dopamine receptors

D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.

Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action.

Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor

Beyond desensitization: physiological relevance of arrestin-dependent signaling.

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917-30

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