UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells - Wikidata - awgldk - TriplyDB

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells

http://www.wikidata.org/entity/Q28248233

about

Beyond T and DHT - novel steroid derivatives capable of wild type androgen receptor activation Unique patterns of molecular profiling between human prostate cancer LNCaP and PC-3 cells Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation Integration of the transcriptome and glycome for identification of glycan cell signatures.Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride.Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor models Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family.Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism.Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis Regulation of UGT2B Expression and Activity by miR-216b-5p in Liver Cancer Cell Lines.Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential.Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors.Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Steroid hormone synthetic pathways in prostate cancer.Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.Characterisations of human prostate stem cells reveal deficiency in class I UGT enzymes as a novel mechanism for castration-resistant prostate cancer.Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels.Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression.Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential.ACSL3 promotes intratumoral steroidogenesis in prostate cancer cells.Stromal TGF-β signaling induces AR activation in prostate cancer.Increased severity of acute graft versus host disease as a result of differential expression following a homozygous gene deletion.Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry.The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys.Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance.

P2860

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P2860

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells

http://www.wikidata.org/entity/Q28248233

description

2007 nî lūn-bûn

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2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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type

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

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P1433

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P1433

Journal of Biological Chemistry

P1476

UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells

@en

P2093

Alain Bélanger

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Olivier Barbier

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Sarah Chouinard

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P2860

Full-length cDNA sequence and genomic organization of human NKX3A - alternative forms and regulation by both androgens and estrogens

Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells

Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids

Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases

Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and Regulation by multiple hormones

Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells

Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium

Endogenous steroid levels in the human prostate from birth to old age: a comparison of normal and diseased tissues

Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme.

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33466-74

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scholarly article

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10.1074/JBC.M703370200

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46

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P478

282

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P577

2007-11-16T00:00:00Z

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P698

17848572

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