Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment
about
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptMetabotropic glutamate receptor 4 in the basal ganglia of parkinsonian monkeys: ultrastructural localization and electrophysiological effects of activation in the striatopallidal complex.Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease.Recent advances in the drug discovery of metabotropic glutamate receptor 4 (mGluR4) activators for the treatment of CNS and non-CNS disorders.Metabotropic glutamate receptor 4 (mGlu4)-positive allosteric modulators for the treatment of Parkinson's disease: historical perspective and review of the patent literature.Recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as CNS therapeutics.Targeting glutamate receptors to tackle the pathogenesis, clinical symptoms and levodopa-induced dyskinesia associated with Parkinson's disease.Therapeutic potential of targeting metabotropic glutamate receptors for Parkinson's disease.Group III metabotropic glutamate receptors and drug addictionTherapeutic potential of targeting glutamate receptors in Parkinson's disease.Group III metabotropic glutamate receptors: pharmacology, physiology and therapeutic potential.Gene expression profiling predicts pathways and genes associated with Parkinson's disease.PINK1 heterozygous mutations induce subtle alterations in dopamine-dependent synaptic plasticity.mGluR4-containing corticostriatal terminals: synaptic interactions with direct and indirect pathway neurons in mice.Metabolic, synaptic and behavioral impact of 5-week chronic deep brain stimulation in hemiparkinsonian rats.Selective and interactive effects of D2 receptor antagonism and positive allosteric mGluR4 modulation on waiting impulsivity.Determination of the absolute configuration of phosphinic analogues of glutamate
P2860
Q35580900-9DF6CE7A-DE24-4979-BBFD-043202F2EA26Q36374309-1E543722-D36A-4900-AFAF-8AABDF30D08DQ37773480-C97C49D9-56BC-405B-87D4-4A8BA3177E74Q37782115-B6E4C355-9574-4DAE-8EEB-B02DC04B1366Q37999106-912D6BC6-3F33-4CBF-A4C1-52153C29EB46Q38002888-1F5D6EE3-7C81-4E42-9ECD-C70FE88B9058Q38031832-77389359-5145-4FE9-BC1E-82B3A82DAAEBQ38056852-0E891206-DC35-44AF-B40A-0F287BBDADD3Q38092819-810AD0BA-F010-433C-9135-550008DEE7BCQ38146898-05B185AE-E3FD-4702-AD02-C9171368D14FQ38190016-E4DFBBFF-9642-4FDA-B939-CD603DE2AC6EQ38242117-93A22328-80EA-476F-B3B8-DDDACCF549E9Q38459136-B7010E42-3ACB-4F8B-827C-CFFFABDEC512Q39647087-E71D62F6-8DD8-4078-8ED5-D005774064F0Q40035243-A9AC7916-54EB-46D3-9E3C-9976D15B79CDQ40313187-898FE5EC-B3EC-46A4-ABF3-EE5F8D1629DCQ41095156-77918F65-DCFD-4DB7-94AF-29AB2F8C414FQ58878103-AEC22B31-D53A-4EE1-9966-8051FD01AFC3
P2860
Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@ast
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@en
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@nl
type
label
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@ast
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@en
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@nl
altLabel
Metabotropic glutamate recepto ...... Parkinson’s disease treatment
@en
prefLabel
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@ast
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@en
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@nl
P2093
P1476
Metabotropic glutamate recepto ...... Parkinson's disease treatment
@en
P2093
Antonio Pisani
Chelliah Selvam
Christophe Melon
Corinne Beurrier
Cyril Goudet
Daniela Vita
Dario Cuomo
Emanuela Barabino
Francine Acher
Giuseppina Martella
P304
P356
10.1111/J.1471-4159.2009.06036.X
P407
P577
2009-05-01T00:00:00Z