Amplification of fgfr4 gene in human breast and gynecological cancers
about
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complexFibroblast growth factor 8 is expressed at higher levels in lactating human breast and in breast cancerFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersDiscovery of Novel Fibroblast Growth Factor Receptor 1 Kinase Inhibitors by Structure-Based Virtual ScreeningTargeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse modelsSimultaneous profiling of 194 distinct receptor transcripts in human cellsSignalling pathways implicated in early mammary gland morphogenesis and breast cancer.Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.Functional FGFR4 Gly388Arg polymorphism contributes to cancer susceptibility: Evidence from meta-analysis.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks.Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancerThe Fibroblast Growth Factor signaling pathwayDifferential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growthTissue-specific regulation of pregnane X receptor in cancer development and therapy.FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancerRationale for targeting fibroblast growth factor receptor signaling in breast cancerFibroblast growth factor receptor 4 polymorphism is associated with liver cirrhosis in hepatocarcinomaExpression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas.Fibroblast growth factor receptor 4 polymorphisms and susceptibility to coronary artery disease.Expression of fibroblast growth factor 1 is lower in breast cancer than in the normal human breast.Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455The location of acidic fibroblast growth factor in the breast is dependent on the activity of proteases present in breast cancer tissueExpression of keratinocyte growth factor and its receptor in human breast cancer.Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new tumour-suppressor genesFGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients.ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.Emerging therapeutic targets in metastatic progression: A focus on breast cancer.Inhibition of Metastatic Potential in Breast Carcinoma In Vivo and In Vitro through Targeting VEGFRs and FGFRs.Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer.Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival.Phase II, randomized, placebo-controlled study of dovitinib in combination with fulvestrant in postmenopausal patients with HR+, HER2- breast cancer that had progressed during or after prior endocrine therapy.Fibroblast growth factors and their receptors in cancer.Fibroblast growth factor receptors (FGFRs) localize in different cellular compartments. A splice variant of FGFR-3 localizes to the nucleus.Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.Deguelin-induced blockade of PI3K/protein kinase B/MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down-regulation of fibroblast growth factor receptor 4 activity.PAX3-FOXO1 and FGFR4 in alveolar rhabdomyosarcoma.Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.Tumoral progression of human breast epithelial cells secreting FGF2 and FGF4.Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis.
P2860
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P2860
Amplification of fgfr4 gene in human breast and gynecological cancers
description
1993 nî lūn-bûn
@nan
1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Amplification of fgfr4 gene in human breast and gynecological cancers
@ast
Amplification of fgfr4 gene in human breast and gynecological cancers
@en
Amplification of fgfr4 gene in human breast and gynecological cancers
@nl
type
label
Amplification of fgfr4 gene in human breast and gynecological cancers
@ast
Amplification of fgfr4 gene in human breast and gynecological cancers
@en
Amplification of fgfr4 gene in human breast and gynecological cancers
@nl
prefLabel
Amplification of fgfr4 gene in human breast and gynecological cancers
@ast
Amplification of fgfr4 gene in human breast and gynecological cancers
@en
Amplification of fgfr4 gene in human breast and gynecological cancers
@nl
P2093
P2860
P3181
P356
P1476
Amplification of fgfr4 gene in human breast and gynecological cancers
@en
P2093
E Armstrong
J Partanen
P Lehtovirta
P Salmikangas
S Jaakkola
S Pyrhönen
P2860
P304
P3181
P356
10.1002/IJC.2910540305
P407
P577
1993-05-28T00:00:00Z