NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation
about
Mast cell activation: a complex interplay of positive and negative signaling pathwaysKit- and Fc epsilonRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cellsThe AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes?Mast cell function: a new vision of an old cell.Adapters in the organization of mast cell signaling.A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responsesRecent advances in the understanding of mastocytosis: the role of KIT mutations.Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release.Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasisNtal/Lab/Lat2.Transmembrane adaptor proteins: organizers of immunoreceptor signalling.Transmembrane adaptor proteins in the high-affinity IgE receptor signalingStem cell factor programs the mast cell activation phenotypeDemonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxisTLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release.Regulation of mast cell responses in health and disease.Mast cell biology: introduction and overview.G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation.Signal transduction and chemotaxis in mast cellsNegative regulation of mast cell signaling and function by the adaptor LAB/NTAL.Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTALSHP-1 deficient mast cells are hyperresponsive to stimulation and critical in initiating allergic inflammation in the lung.Cross-talk between tetraspanin CD9 and transmembrane adaptor protein non-T cell activation linker (NTAL) in mast cell activation and chemotaxis.A tale of two TRAPs: LAT and LAB in the regulation of lymphocyte development, activation, and autoimmunityMast cells and mastocytosis.Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders.Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.The tyrosine kinase network regulating mast cell activation.Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release.Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activationActivation and function of the mTORC1 pathway in mast cellsAmplification mechanisms for the enhancement of antigen-mediated mast cell activation.New insights on mast cell activation via the high affinity receptor for IgERegulation of lymphocyte development and activation by the LAT family of adapter proteins.Tec family kinases: regulation of FcεRI-mediated mast-cell activation.Immunoglobulin E receptor signaling and asthmaMastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease.
P2860
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P2860
NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@ast
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@en
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@nl
type
label
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@ast
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@en
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@nl
prefLabel
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@ast
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@en
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@nl
P2093
P1433
P1476
NTAL phosphorylation is a pivo ...... and Fc epsilon RI aggregation
@en
P2093
Alasdair M Gilfillan
Anne B Satterthwaite
Christine Tkaczyk
Dean D Metcalfe
Dong-Ho Nahm
Lawrence E Samelson
Petr Draber
Shoko Iwaki
Vaclav Horejsi
P304
P356
10.1182/BLOOD-2003-08-2769
P407
P577
2004-07-01T00:00:00Z