Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
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Deficient expression of DNA repair enzymes in early progression to sporadic colon cancerEpigenetic field defects in progression to cancerRefining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variantsThe clinical phenotype of Lynch syndrome due to germ-line PMS2 mutationsPMS2 monoallelic mutation carriers: the known unknownNovel diet-related mouse model of colon cancer parallels human colon cancerEpigenetic reduction of DNA repair in progression to gastrointestinal cancerCombined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group StudyPartial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers.Stabilization of mismatch repair gene PMS2 by glycogen synthase kinase 3beta is implicated in the treatment of cervical carcinomaSorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study.Transactional database transformation and its application in prioritizing human disease genes.The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedsideA comprehensive look at transcription factor gene expression changes in colorectal adenomas.Hereditary Non-Polyposis Colorectal Cancer: the rise and fall of a confusing term.Familial colorectal cancer: eleven years of data from a registry program in Switzerland.Involvement of p53 mutation and mismatch repair proteins dysregulation in NNK-induced malignant transformation of human bronchial epithelial cellsLow frequency of Lynch syndrome among young patients with non-familial colorectal cancer.Differential MSH2 promoter methylation in blood cells of Neurofibromatosis type 1 (NF1) patientsDifferential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status.A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome.Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancer.Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.Functional PMS2 hybrid alleles containing a pseudogene-specific missense variant trace back to a single ancient intrachromosomal recombination event.Preinvasive colorectal lesion transcriptomes correlate with endoscopic morphology (polypoid vs. nonpolypoid).Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiencyImproved multiplex ligation-dependent probe amplification analysis identifies a deleterious PMS2 allele generated by recombination with crossover between PMS2 and PMS2CL.Recurrent and founder mutations in the PMS2 gene.Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.Immunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency.Structure and function of the components of the human DNA mismatch repair system.Patients with an unexplained microsatellite instable tumour have a low risk of familial cancerHuman postmeiotic segregation 2 exhibits biased repair at tetranucleotide microsatellite sequencesDifferences and evolution of the methods for the assessment of microsatellite instability.Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasiaThe Norwegian PMS2 founder mutation c.989-1G > T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry.Genetic counseling considerations in the evaluation of families for Lynch syndrome--a review.Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium 'care for CMMRD' (C4CMMRD).Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort.Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis.
P2860
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P2860
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
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2005 nî lūn-bûn
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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
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name
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@ast
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@en
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
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Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@ast
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@en
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@nl
prefLabel
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@ast
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@en
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@nl
P2093
P1433
P1476
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
@en
P2093
Anna Russell
Fridolin Bannwart
Giancarlo Marra
Hans-Martin Riehle
Hueseyin Yurtsever
Jan-Olaf Gebbers
Joerg Neuweiler
Josef Jiricny
Judith Luz
Karl Heinimann
P304
P356
10.1053/J.GASTRO.2005.01.056
P407
P50
P577
2005-05-01T00:00:00Z