Crystal structure of a type III pantothenate kinase: insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria
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Structure of the Type III Pantothenate Kinase from Bacillus anthracis at 2.0 Å Resolution: Implications for Coenzyme A-Dependent Redox Biology † , ‡Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorderStructural and Biochemical Characterization of Compounds Inhibiting Mycobacterium tuberculosis Pantothenate KinaseSequence and structural analysis of the Asp-box motif and Asp-box beta-propellers; a widespread propeller-type characteristic of the Vps10 domain family and several glycoside hydrolase familiesNucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase.Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.Differential effects of a mutation on the normal and promiscuous activities of orthologs: implications for natural and directed evolution.Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea.The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.Small Molecule Restores Itaconate Sensitivity in Salmonella enterica: A Potential New Approach to Treating Bacterial Infections.The type III pantothenate kinase encoded by coaX is essential for growth of Bacillus anthracisRecent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development.Coenzyme A biosynthetic machinery in mammalian cells.Regulation of Coenzyme A Biosynthesis in the Hyperthermophilic Bacterium Thermotoga maritima.Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.Bacterial protein structures reveal phylum dependent divergence.PanG, a new ketopantoate reductase involved in pantothenate synthesis.Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target.Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.Screening, identification, and characterization of mechanistically diverse inhibitors of the Mycobacterium tuberculosis enzyme, pantothenate kinase (CoaA).
P2860
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P2860
Crystal structure of a type III pantothenate kinase: insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria
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2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2006 թվականի օգոստոսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Crystal structure of a type II ...... rsally distributed in bacteria
@ast
Crystal structure of a type II ...... rsally distributed in bacteria
@en
Crystal structure of a type II ...... rsally distributed in bacteria
@nl
type
label
Crystal structure of a type II ...... rsally distributed in bacteria
@ast
Crystal structure of a type II ...... rsally distributed in bacteria
@en
Crystal structure of a type II ...... rsally distributed in bacteria
@nl
prefLabel
Crystal structure of a type II ...... rsally distributed in bacteria
@ast
Crystal structure of a type II ...... rsally distributed in bacteria
@en
Crystal structure of a type II ...... rsally distributed in bacteria
@nl
P2093
P2860
P356
P1476
Crystal structure of a type II ...... rsally distributed in bacteria
@en
P2093
Dariusz Martynowski
Hong Zhang
Leisl A Brand
Yvonne Eyobo
P2860
P304
P356
10.1128/JB.00469-06
P407
P577
2006-08-01T00:00:00Z