HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A - Wikidata - awgldk - TriplyDB

HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A

HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A

http://www.wikidata.org/entity/Q28253208

about

Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression SET-related cell division autoantigen-1 (CDA1) arrests cell growth Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia Protein ligands to HuR modulate its interaction with target mRNAs in vivo Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals Arsenic sulfide promotes apoptosis in retinoid acid resistant human acute promyelocytic leukemic NB4-R1 cells through downregulation of SET protein A role for the nucleosome assembly proteins TAF-Iβ and NAP1 in the activation of BZLF1 expression and Epstein-Barr virus reactivation Heterogeneous nuclear ribonucleoprotein A2 is a SET-binding protein and a PP2A inhibitor.Proteomic analysis of SET-binding proteins.Mll rearrangements in haematological malignancies: lessons from clinical and biological studies.Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines.Sperm chromatin decondensation by template activating factor I through direct interaction with basic proteins.The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiation Protein phosphatase 2A activity affects histone H3 phosphorylation and transcription in Drosophila melanogaster.spr-2, a suppressor of the egg-laying defect caused by loss of sel-12 presenilin in Caenorhabditis elegans, is a member of the SET protein subfamily.SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia.A quantitative proteomic analysis of mitochondrial participation in p19 cell neuronal differentiation.Mixed lineage leukemia: roles in human malignancies and potential therapy.Synergistic action of MLL, a TRX protein with template activating factor-I, a histone chaperone.PP2A as a master regulator of the cell cycle.Tetra-arsenic tetra-sulfide (As4S 4) promotes apoptosis in retinoid acid -resistant human acute promyelocytic leukemic NB4-R1 cells through downregulation of SET protein.Secretome proteins as candidate biomarkers for aggressive thyroid carcinomas.SET-induced calcium signaling and MAPK/ERK pathway activation mediate dendritic cell-like differentiation of U937 cells.Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937.PHAPI/pp32 suppresses tumorigenesis by stimulating apoptosis.The nuclear localization of SET mediated by impalpha3/impbeta attenuates its cytosolic toxicity in neurons.Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos.Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways.Arabidopsis NRP1 and NRP2 encode histone chaperones and are required for maintaining postembryonic root growth.

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P2860

HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A

http://www.wikidata.org/entity/Q28253208

description

1997 nî lūn-bûn

@nan

1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

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1997年論文

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1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

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name

HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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type

label

HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

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prefLabel

HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

@ast

HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

@en

HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

@nl

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JBC.272.45.28407

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Journal of Biological Chemistry

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HRX leukemic fusion proteins f ...... SET and protein phosphatase 2A

@en

P2093

D C Tkachuk

http://www.w3.org/2001/XMLSchema#string

F S Nallaseth

http://www.w3.org/2001/XMLSchema#string

G Walter

http://www.w3.org/2001/XMLSchema#string

H T Adler

http://www.w3.org/2001/XMLSchema#string

P2860

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A

Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains

Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

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28407-14

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scholarly article

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10.1074/JBC.272.45.28407

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45

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272

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9353299

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