The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor
about
Macrocyclic histone deacetylase inhibitorsImproved total synthesis of the potent HDAC inhibitor FK228 (FR-901228)Small molecule inhibitors of zinc-dependent histone deacetylasesHistone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited successAnticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells.Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.Interpreting clinical assays for histone deacetylase inhibitors.Romidepsin (Istodax, NSC 630176, FR901228, FK228, depsipeptide): a natural product recently approved for cutaneous T-cell lymphomaHuman endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latencyIsoform-selective histone deacetylase inhibitorsChromobacterium violaceum and its important metabolites--review.Pharmacological inhibition of histone deacetylases for the treatment of cancer, neurodegenerative disorders and inflammatory diseases.Trend of histone deacetylase inhibitors in cancer therapy: isoform selectivity or multitargeted strategy.Disulfide-bridged peptide macrobicycles from nature.Low-dose spiruchostatin-B, a potent histone deacetylase inhibitor enhances radiation-induced apoptosis in human lymphoma U937 cells via modulation of redox signaling.A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes.CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.Natural product analogues: towards a blueprint for analogue-focused synthesis.Non-peptide macrocyclic histone deacetylase inhibitors.Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis.Effect of ester chemical structure and peptide bond conformation in fragmentation pathways of differently metal cationized cyclodepsipeptides.Marine Peptides and Proteins with Cytotoxic and Antitumoral Properties
P2860
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P2860
The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The first biologically active ...... histone deacetylase inhibitor
@ast
The first biologically active ...... histone deacetylase inhibitor
@en
The first biologically active ...... histone deacetylase inhibitor
@nl
type
label
The first biologically active ...... histone deacetylase inhibitor
@ast
The first biologically active ...... histone deacetylase inhibitor
@en
The first biologically active ...... histone deacetylase inhibitor
@nl
prefLabel
The first biologically active ...... histone deacetylase inhibitor
@ast
The first biologically active ...... histone deacetylase inhibitor
@en
The first biologically active ...... histone deacetylase inhibitor
@nl
P2093
P50
P3181
P356
P1476
The first biologically active ...... histone deacetylase inhibitor
@en
P2093
Alex Hon Kit Mo
Alexander Richard Liam Cecil
Alexander Yurek-George
Fay Habens
Helen Rogers
Satoko Maeda
P304
P3181
P356
10.1021/JM0703800
P407
P577
2007-10-24T00:00:00Z