RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR - Wikidata - awgldk - TriplyDB

RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR

RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR

http://www.wikidata.org/entity/Q28256487

about

A diverse range of gene products are effectors of the type I interferon antiviral response Constraints on the Genetic and Antigenic Variability of Measles Virus Adenosine-to-inosine RNA editing and human disease Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication Enhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinase Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer.Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1.An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).Molecular diversity through RNA editing: a balancing act.The RNA editor gene ADAR1 is induced in myoblasts by inflammatory ligands and buffers stress response.Interplay between innate immunity and negative-strand RNA viruses: towards a rational model Tudor-SN and ADAR1 are components of cytoplasmic stress granules.Substitutional A-to-I RNA editing.Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells.Adenosine deaminases acting on RNA, RNA editing, and interferon action.Prediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences.Comparative mutational analyses of influenza A viruses.Host response to polyomavirus infection is modulated by RNA adenosine deaminase ADAR1 but not by ADAR2 Adenosine deaminase acting on RNA 1 (ADAR1) suppresses the induction of interferon by measles virus.ADAR1 Facilitates HIV-1 Replication in Primary CD4+ T Cells Measles Virus Defective Interfering RNAs Are Generated Frequently and Early in the Absence of C Protein and Can Be Destabilized by Adenosine Deaminase Acting on RNA-1-Like Hypermutations.STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1 A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection.dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection.Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection Stress granule formation induced by measles virus is protein kinase PKR dependent and impaired by RNA adenosine deaminase ADAR1 Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1 ADARs: viruses and innate immunity.RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment.Measles virus C protein impairs production of defective copyback double-stranded viral RNA and activation of protein kinase R.ADAR1 deaminase contributes to scheduled skeletal myogenesis progression via stage-specific functions.Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus.ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element.Adenosine-to-inosine RNA editing meets cancer.Site-selective versus promiscuous A-to-I editing.

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P2860

RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR

http://www.wikidata.org/entity/Q28256487

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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JBC.M109.045146

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Journal of Biological Chemistry

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RNA-specific adenosine deamina ...... tivation of protein kinase PKR

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P2093

Ann M Toth

http://www.w3.org/2001/XMLSchema#string

Charles E Samuel

http://www.w3.org/2001/XMLSchema#string

Zhiqun Li

http://www.w3.org/2001/XMLSchema#string

P2860

New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1

Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase

Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

Inhibition of hepatitis delta virus RNA editing by short inhibitory RNA-mediated knockdown of ADAR1 but not ADAR2 expression.

Antiviral actions of interferons

Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase

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29350-6

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10.1074/JBC.M109.045146

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43

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284

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Roberto Cattaneo

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19710021

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2785566

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