An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
about
Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tagKinases as druggable targets in trypanosomatid protozoan parasitesPlasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2.An essential malaria protein defines the architecture of blood-stage and transmission-stage parasites.Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime RegionReceptor for Activated C-Kinase 1 (PfRACK1) is required for Plasmodium falciparum intra-erythrocytic proliferationA tetracycline-repressible transactivator system to study essential genes in malaria parasitesFunctional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparumATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruptionCharacterization of the small exported Plasmodium falciparum membrane protein SEMP1A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversionErythrocyte lysis and Xenopus laevis oocyte rupture by recombinant Plasmodium falciparum hemolysin IIIFunctional characterization of a SUMO deconjugating protease of Plasmodium falciparum using newly identified small molecule inhibitorsPlasmodium falciparum heterochromatin protein 1 binds to tri-methylated histone 3 lysine 9 and is linked to mutually exclusive expression of var genesSAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodium falciparumExonuclease-mediated degradation of nascent RNA silences genes linked to severe malariaRecent advances in malaria genomics and epigenomicsIdentification and characterization of a liver stage-specific promoter region of the malaria parasite PlasmodiumSystematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparumIntracellular context affects levels of a chemically dependent destabilizing domainInducible knockdown of Plasmodium gene expression using the glmS ribozymeCRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein functionUse of peptide nucleic acids to manipulate gene expression in the malaria parasite Plasmodium falciparumInvestigation of the Plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT)Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeletonA genetic system to study Plasmodium falciparum protein functionA transcriptional switch underlies commitment to sexual development in malaria parasitesPlasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial feversA plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytesInhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont developmentPlasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogonyMolecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites.Improved conditional expression systems resulting in physiological level of HNF4alpha expression confirm HNF4alpha induced apoptosis in the pancreatic beta-cell line INS-1.Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.A research agenda for malaria eradication: basic science and enabling technologiesPfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.Destabilization domain approach adapted for regulated protein expression in the protozoan parasite Entamoeba histolytica.Maurer's clefts, the enigma of Plasmodium falciparum.Versatile control of Plasmodium falciparum gene expression with an inducible protein-RNA interaction2A and the auxin-based degron system facilitate control of protein levels in Plasmodium falciparum.
P2860
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P2860
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@ast
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@en
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@nl
type
label
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@ast
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@en
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@nl
prefLabel
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@ast
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@en
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@nl
P3181
P356
P1433
P1476
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum
@en
P2093
Christopher M Armstrong
Daniel E Goldberg
P2888
P304
P3181
P356
10.1038/NMETH1132
P407
P577
2007-12-01T00:00:00Z
P6179
1020723366