Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
about
PEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseasesHuman testicular peritubular cells secrete pigment epithelium-derived factor (PEDF), which may be responsible for the avascularity of the seminiferous tubules.Pericytes, an overlooked player in vascular pathobiologyPigment epithelium-derived factor (PEDF) as a therapeutic target in cardiovascular diseaseHypoxia-induced upregulation of pigment epithelium-derived factor by retinal glial (Müller) cellsExpression of vascular endothelial growth factor and pigment epithelial-derived factor in a rat model of retinopathy of prematurityA therapeutic strategy for choroidal neovascularization based on recruitment of mesenchymal stem cells to the sites of lesions.Clinical correlates of serum pigment epithelium-derived factor in type 2 diabetes patients.Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective.Renal tubular angiogenic dysregulation in anti-Thy1.1 glomerulonephritis.Overexpression of pigment epithelium-derived factor inhibits retinal inflammation and neovascularization.Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR-γ-related pharmacology.Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: role of NADPH oxidase 4.Effects of intravitreal triamcinolone acetonide on retinal gene expression in a rat model of central retinal vein occlusion.Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/beta-catenin signaling pathway and uPAR expression.PEDF regulates vascular permeability by a γ-secretase-mediated pathway.Panretinal photocoagulation (PRP) versus PRP plus intravitreal ranibizumab for high-risk proliferative diabetic retinopathy.Effect of intravitreal anti-vascular endothelial growth factor treatment on the retinal gene expression in acute experimental central retinal vein occlusion.The potential of nanomedicine therapies to treat neovascular disease in the retina.Antiangiogenic therapy for ischemic retinopathies.Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathyEffects of arteriolar constriction on retinal gene expression and Müller cell responses in a rat model of branch retinal vein occlusion.A PEDF-derived peptide inhibits retinal neovascularization and blocks mobilization of bone marrow-derived endothelial progenitor cellsAngiogenesis in diabetes and obesityPigment epithelium-derived factor mediates impaired lung vascular development in neonatal hyperoxia.Attenuation of choroidal neovascularization by histone deacetylase inhibitor.Increased serum pigment epithelium-derived factor in women with gestational diabetes is associated with type 2 diabetes.Co-culture of Retinal and Endothelial Cells Results in the Modulation of Genes Critical to Retinal NeovascularizationCell and molecular biology underpinning the effects of PEDF on cancers in general and osteosarcoma in particular.Aqueous humor concentrations of vascular endothelial growth factor and pigment epithelium-derived factor in high myopic patients.Adenoviral 15-lipoxygenase-1 gene transfer inhibits hypoxia-induced proliferation of retinal microvascular endothelial cells in vitroOverexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression.Administration of Pigment Epithelium-Derived Factor Inhibits Airway Inflammation and Remodeling in Chronic OVA-Induced Mice via VEGF Suppression.Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathyPigment epithelium-derived factor (PEDF) peptide eye drops reduce inflammation, cell death and vascular leakage in diabetic retinopathy in Ins2(Akita) mice.INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASERetinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathyPotential therapeutic effects of pigment epithelium-derived factor for treatment of diabetic retinopathyStrategies for blocking angiogenesis in diabetic retinopathy: from basic science to clinical practice.
P2860
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P2860
Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@ast
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@en
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@nl
type
label
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@ast
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@en
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@nl
prefLabel
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@ast
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@en
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@nl
P2093
P3181
P356
P1476
Pigment epithelium-derived fac ...... inding in diabetic retinopathy
@en
P2093
Guoquan Gao
Jian-xing Ma
Joshua J Wang
Kyoungmin Parke
Sarah X Zhang
P3181
P356
10.1677/JME.1.02008
P407
P577
2006-08-01T00:00:00Z