Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
about
Ubiquitin-proteasome system involvement in Huntington's diseaseMutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degenerationMutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathwayPathways towards and away from Alzheimer's diseaseAge-related gene-specific changes of A-to-I mRNA editing in the human brainPresenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylationTranscriptional slippage in bacteria: distribution in sequenced genomes and utilization in IS element gene expressionIt Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer DiseaseThe Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord InjuryMisframed ubiquitin and impaired protein quality control: an early event in Alzheimer's diseaseRibosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious useHeritable change caused by transient transcription errorsStructural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and NeurotoxicityAlternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markersThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseasePhosphorylation of the histone deacetylase 7 modulates its stability and association with 14-3-3 proteinsArgyrophilic grain diseaseThe ubiquitin-proteasome system in Alzheimer's diseaseRegulatory mechanisms involved in the control of ubiquitin homeostasisTranslational misreading: a tRNA modification counteracts a +2 ribosomal frameshiftThe ubiquitin-proteasome pathway and proteasome inhibitorsThe ubiquitin proteasome system in glia and its role in neurodegenerative diseasesTop-down proteomics with mass spectrometry imaging: a pilot study towards discovery of biomarkers for neurodevelopmental disordersThe ubiquitin-proteasome pathway: on protein death and cell lifeSpermidine protects against α-synuclein neurotoxicity.Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.A survey of RNA editing in human brainUnexpected frameshifts from gene to expressed protein in a phage-displayed peptide libraryA dinucleotide deletion in amyloid precursor protein (APP) mRNA associated with sporadic Alzheimer's disease results in efficient secretion of truncated APP isoforms from neuroblastoma cell cultures.Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains.Role of the ubiquitin proteasome system in Alzheimer's disease.Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.Misincorporation by RNA polymerase is a major source of transcription pausing in vivoTau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Genetic risk factors in Alzheimer's diseaseThe study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder.Selective Transgenic Expression of Mutant Ubiquitin in Purkinje Cell Stripes in the Cerebellum.APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis
P2860
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P2860
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@ast
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@de
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@en
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@fr
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@nl
type
label
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@ast
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@de
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@en
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@fr
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@nl
prefLabel
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@ast
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@de
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@en
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@fr
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@nl
P2093
P3181
P1433
P1476
Frameshift mutants of beta amy ...... Alzheimer's and Down patients
@en
P2093
A Neubauer
D P de Kleijn
F G Grosveld
F W van Leeuwen
G J Martens
H H van den Hurk
J A Sluijs
M A Sonnemans
P304
P3181
P356
10.1126/SCIENCE.279.5348.242
P407
P577
1998-01-01T00:00:00Z