Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression
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Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional studyInduction of P-450 in workers exposed to dioxinHuman CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLPSignatures of natural selection in the human genomeMolecular genetics of the human cytochrome P450 monooxygenase superfamilyFunctional evaluation of genetic and environmental regulators of p450 mRNA levelsToward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locusPolymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerCytochrome P450 1A2 detoxicates aristolochic acid in the mouse.Computational and in vitro studies on the inhibitory effects of herbal compounds on human cytochrome P450 1A2.Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.Cellular responses to oxidative stress: the [Ah] gene battery as a paradigm.Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study.ord1, an oxidoreductase gene responsible for conversion of O-methylsterigmatocystin to aflatoxin in Aspergillus flavus.Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women.Effects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients.The Impact of CYP1A2 and CYP2E1 Genes Polymorphism on Theophylline ResponseA Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.Activation of aflatoxin B1 by expression of human CYP1A2 polymorphisms in Saccharomyces cerevisiae.Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing.Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans.Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa.Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms.DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection.CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics.Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.Hormonal regulation of CYP1A expression.Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid.Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2'-dimethyl-4-aminobiphenyl (DMABGenetic polymorphisms in human drug-metabolizing enzymes: potential uses of reverse genetics to identify genes of toxicological relevance.Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine.Simplified approach for evaluation of hepatic drug-oxidizing capacity with a simultaneous measurement of caffeine and its primary demethylated metabolites in carbon tetrachloride-intoxicated rats.Engineering the metabolism of the phenylurea herbicide chlortoluron in genetically modified Arabidopsis thaliana plants expressing the mammalian cytochrome P450 enzyme CYP1A2.Effects of the aqueous extract from Salvia miltiorrhiza Bunge on caffeine pharmacokinetics and liver microsomal CYP1A2 activity in humans and rats.Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.CYP1A2 genotype affects carbamazepine pharmacokinetics in children with epilepsy.
P2860
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P2860
Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression
description
1989 nî lūn-bûn
@nan
1989 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@ast
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@en
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@nl
type
label
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@ast
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@en
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@nl
prefLabel
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@ast
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@en
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@nl
P2093
P356
P1476
Human CYP1A2: sequence, gene s ...... s in liver 1A2 mRNA expression
@en
P2093
P304
P356
10.1210/MEND-3-9-1399
P407
P577
1989-09-01T00:00:00Z