PIKfyve negatively regulates exocytosis in neurosecretory cells
about
Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella.Phosphatidylinositol 3,5-bisphosphate: low abundance, high significanceLipid kinases as therapeutic targets for chronic painInhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell deathCa2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesiclesMyosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin.Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P₂ and PI(5)PEarly to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells.Endosomal phosphoinositides and human diseases.Lipids in Regulated Exocytosis: What are They Doing?Function and dysfunction of the PI system in membrane trafficking.Abrogating Munc18-1-SNARE complex interaction has limited impact on exocytosis in PC12 cells.The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.Lipids implicated in the journey of a secretory granule: from biogenesis to fusion.Class II phosphoinositide 3-kinase C2alpha: what we learned so farTargeting the glial-derived neurotrophic factor and related molecules for controlling normal and pathologic pain.PIKfyve inhibition increases exosome release and induces secretory autophagy.PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.Lipid remodelling in neuroendocrine secretion.Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells.
P2860
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P2860
PIKfyve negatively regulates exocytosis in neurosecretory cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
PIKfyve negatively regulates exocytosis in neurosecretory cells
@ast
PIKfyve negatively regulates exocytosis in neurosecretory cells
@en
PIKfyve negatively regulates exocytosis in neurosecretory cells
@nl
type
label
PIKfyve negatively regulates exocytosis in neurosecretory cells
@ast
PIKfyve negatively regulates exocytosis in neurosecretory cells
@en
PIKfyve negatively regulates exocytosis in neurosecretory cells
@nl
prefLabel
PIKfyve negatively regulates exocytosis in neurosecretory cells
@ast
PIKfyve negatively regulates exocytosis in neurosecretory cells
@en
PIKfyve negatively regulates exocytosis in neurosecretory cells
@nl
P2093
P2860
P50
P356
P1476
PIKfyve negatively regulates exocytosis in neurosecretory cells
@en
P2093
Christine Boucheron
Hao N Nguyen
Hiroyuki Kaizawa
Masahiko Hayakawa
Peter J Wen
Shona L Osborne
P2860
P304
P356
10.1074/JBC.M704856200
P407
P577
2008-02-01T00:00:00Z