Parkin interacts with the proteasome subunit alpha4 - Wikidata - awgldk - TriplyDB

Parkin interacts with the proteasome subunit alpha4

Parkin interacts with the proteasome subunit alpha4

http://www.wikidata.org/entity/Q28259006

about

RBR E3 ubiquitin ligases: new structures, new insights, new questions Parkin occurs in a stable, non-covalent, approximately 110-kDa complex in brain Oligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition.Mdm2 facilitates the association of p53 with the proteasome.Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity.The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13 Heterogeneous cardiac proteasomes: mandated by diverse substrates?Parkinson's disease, proteins, and prions: milestones.Parkin, A Top Level Manager in the Cell's Sanitation Department.Proteins directly interacting with mammalian 20S proteasomal subunits and ubiquitin-independent proteasomal degradation Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro.Dyrk1A phosphorylates parkin at Ser-131 and negatively regulates its ubiquitin E3 ligase activity.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.Differential effects of Parkin and its mutants on protein aggregation, the ubiquitin-proteasome system, and neuronal cell death in human neuroblastoma cells.Long-term overexpression of human wild-type and T240R mutant Parkin in rat substantia nigra induces progressive dopaminergic neurodegeneration.Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.Mechanistic contributions of FBXO7 to Parkinson disease.EGFR trafficking: parkin' in a jam

P2860

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P2860

Parkin interacts with the proteasome subunit alpha4

http://www.wikidata.org/entity/Q28259006

description

2005 nî lūn-bûn

@nan

2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Parkin interacts with the proteasome subunit alpha4

@ast

Parkin interacts with the proteasome subunit alpha4

@en

Parkin interacts with the proteasome subunit alpha4

@nl

type

label

Parkin interacts with the proteasome subunit alpha4

@ast

Parkin interacts with the proteasome subunit alpha4

@en

Parkin interacts with the proteasome subunit alpha4

@nl

prefLabel

Parkin interacts with the proteasome subunit alpha4

@ast

Parkin interacts with the proteasome subunit alpha4

@en

Parkin interacts with the proteasome subunit alpha4

@nl

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P356

J.FEBSLET.2005.06.003

P1433

P1476

Parkin interacts with the proteasome subunit alpha4

@en

P2093

A Yamamoto

http://www.w3.org/2001/XMLSchema#string

C B Lücking

http://www.w3.org/2001/XMLSchema#string

C Hampe

http://www.w3.org/2001/XMLSchema#string

E Casademunt

http://www.w3.org/2001/XMLSchema#string

E E Wanker

http://www.w3.org/2001/XMLSchema#string

E Schultz

http://www.w3.org/2001/XMLSchema#string

J C Dächsel

http://www.w3.org/2001/XMLSchema#string

K Vaupel

http://www.w3.org/2001/XMLSchema#string

M Dichgans

http://www.w3.org/2001/XMLSchema#string

M Lalowski

http://www.w3.org/2001/XMLSchema#string

P2860

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

How does parkin ligate ubiquitin to Parkinson's disease?

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

Structure of 20S proteasome from yeast at 2.4 A resolution

Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex

Association between early-onset Parkinson's disease and mutations in the parkin gene

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

P304

3913-9

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scholarly article

P356

10.1016/J.FEBSLET.2005.06.003

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P407

P433

18

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P478

579

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2005-07-18T00:00:00Z

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7755659

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15987638

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