Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage
about
ASARM peptides: PHEX-dependent and -independent regulation of serum phosphateExtracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemiaOsteocytes: master orchestrators of boneRegulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathwayA unified model for bone-renal mineral and energy metabolismThe Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteinsRegulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)Using the RosettaSurface algorithm to predict protein structure at mineral surfaces.PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolismAbnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin.Adaptive evolution of the matrix extracellular phosphoglycoprotein in mammalsCooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblastsPhosphorylation-dependent mineral-type specificity for apatite-binding peptide sequencesMEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemiaThe impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.SPR4-peptide alters bone metabolism of normal and HYP mice.ASARM mineralization hypothesis: a bridge too far?Partial high-resolution structure of phosphorylated and non-phosphorylated leucine-rich amelogenin protein adsorbed to hydroxyapatite.Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: identification as an allele of 'Hyp'.Proteomic database mining opens up avenues utilizing extracellular protein phosphorylation for novel therapeutic applications.Inhibition of osteoblast mineralization by phosphorylated phage-derived apatite-specific peptidePost-translational modification of osteopontin: effects on in vitro hydroxyapatite formation and growth.Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motifNormocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study.The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled.New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.Family with sequence similarity member 20C is the primary but not the only kinase for the small-integrin-binding ligand N-linked glycoproteins in boneAlkaline Phosphatase and Hypophosphatasia.Osteopontin protects against high phosphate-induced nephrocalcinosis and vascular calcification.Insights from genetic disorders of phosphate homeostasisIn vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontinPolyphosphates inhibit extracellular matrix mineralization in MC3T3-E1 osteoblast cultures.Directing lineage specification of human mesenchymal stem cells by decoupling electrical stimulation and physical patterning on unmodified grapheneThe rachitic tooth.Ablation of osteopontin improves the skeletal phenotype of phospho1(-/-) mice.Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice.Therapeutic management of hypophosphatemic rickets from infancy to adulthood.
P2860
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P2860
Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@ast
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@en
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@nl
type
label
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@ast
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@en
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@nl
prefLabel
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@ast
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@en
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@nl
P2093
P3181
P356
P1476
Phosphorylation-dependent inhi ...... is regulated by PHEX cleavage
@en
P2093
David L Masica
Marc D McKee
William N Addison
P304
P3181
P356
10.1359/JBMR.090832
P407
P577
2010-04-01T00:00:00Z