Modulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanisms
about
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal modelsAmyloid β-Protein Assembly: The Effect of Molecular Tweezers CLR01 and CLR03Resveratrol and Alzheimer's disease: message in a bottle on red wine and cognition.Toll-like receptor 4-mediated signaling participates in apoptosis of hippocampal neurons.Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity.Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers.Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose on Amyloid β25-35 Assembly.Diaryl hydrazones as multifunctional inhibitors of amyloid self-assembly.Conformational Ensemble of hIAPP Dimer: Insight into the Molecular Mechanism by which a Green Tea Extract inhibits hIAPP Aggregation.Intrinsically disordered proteins and novel strategies for drug discovery.Clearance of extracellular misfolded proteins in systemic amyloidosis: experience with transthyretin.Structural, morphological, and functional diversity of amyloid oligomers.Eukaryotic aggresomes: from a model of conformational diseases to an emerging type of immobilized biocatalyzers.Partial peptide of α-synuclein modified with small-molecule inhibitors specifically inhibits amyloid fibrillation of α-synuclein.Molecular tweezers for lysine and arginine - powerful inhibitors of pathologic protein aggregationDiscovery of Small Molecules that Induce the Degradation of Huntingtin.1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose Binds to the N-terminal Metal Binding Region to Inhibit Amyloid β-protein Oligomer and Fibril Formation.para-Sulfonatocalix[n]arenes Inhibit Amyloid β-Peptide Fibrillation and Reduce Amyloid Cytotoxicity.Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds.Resveratrol Attenuates Aβ-Induced Early Hippocampal Neuron Excitability Impairment via Recovery of Function of Potassium Channels.Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation.Synthesis and conformational studies of a stable peptidomimetic β-hairpin based on a bifunctional diketopiperazine turn inducer
P2860
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P2860
Modulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanisms
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Modulating self-assembly of am ...... ses: strategies and mechanisms
@ast
Modulating self-assembly of am ...... ses: strategies and mechanisms
@en
Modulating self-assembly of am ...... ses: strategies and mechanisms
@nl
type
label
Modulating self-assembly of am ...... ses: strategies and mechanisms
@ast
Modulating self-assembly of am ...... ses: strategies and mechanisms
@en
Modulating self-assembly of am ...... ses: strategies and mechanisms
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prefLabel
Modulating self-assembly of am ...... ses: strategies and mechanisms
@ast
Modulating self-assembly of am ...... ses: strategies and mechanisms
@en
Modulating self-assembly of am ...... ses: strategies and mechanisms
@nl
P2860
P3181
P356
P1433
P1476
Modulating self-assembly of am ...... ses: strategies and mechanisms
@en
P2093
P2860
P304
P3181
P356
10.1002/CMDC.201100585
P407
P577
2012-03-05T00:00:00Z