The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction

The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction

Item
http://www.wikidata.org/entity/Q28259912
Regulation of BOB.1/OBF.1 stability by SIAHCoactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA.Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development.The Ets factor Spi-B is a direct critical target of the coactivator OBF-1Oct1 and OCA-B are selectively required for CD4 memory T cell functionB and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6Different N-terminal isoforms of Oct-1 control expression of distinct sets of genes and their high levels in Namalwa Burkitt's lymphoma cells affect a wide range of cellular processes.BOB.1/OBF.1 deficiency affects marginal-zone B-cell compartment.Btk expression is controlled by Oct and BOB.1/OBF.1.Expression of B-lymphocyte-associated transcription factors in human T-cell neoplasms.Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB.BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responses.NF-κB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells.Germline variation in the 3'-untranslated region of the POU2AF1 gene is associated with susceptibility to lymphoma.
P2860

The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction

Item
http://www.wikidata.org/entity/Q28259912
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@ast
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@en
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@nl
type
label
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@ast
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@en
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@nl
prefLabel
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@ast
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@en
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P577
P698
P3181
P356
P1433
P1476
The B cell-specific coactivato ...... nsable for IL-2 gene induction
@en
P2093
P304
P31
P3181
P356
10.1016/S0171-2985(97)80041-1
P407
P433
P478
P577
P698