Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?
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The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migrationThe actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasionMigrastatin analogues target fascin to block tumour metastasisProinvasion metastasis drivers in early-stage melanoma are oncogenes.miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancerTumor self-seeding by circulating cancer cellsThe interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasionMechanism of Actin Filament Bundling by FascinMolecular Mechanism of Fascin Function in Filopodial FormationNOX1 supports the metabolic remodeling of HepG2 cellsThe small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.Ena/VASP proteins have an anti-capping independent function in filopodia formation.Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasisFascin1 is dispensable for mouse development but is favorable for neonatal survivalRhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C.Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation.Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture.A simplicial complex-based approach to unmixing tumor progression data.Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas.Fascin expression in skull base chordoma: correlation with tumor recurrence and dura erosion.Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade.Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1.Involvement of CYR61 and CTGF in the fascin-mediated proliferation and invasiveness of esophageal squamous cell carcinomas cells.Fascin over expression is associated with dysplastic changes in sinonasal inverted papillomas: a study of 47 cases.Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasisDiverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analogActin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodiaAssociation of Fascin and matrix metalloproteinase-9 expression with poor prognostic parameters in breast carcinoma of Egyptian women.Fascin expression in pleomorphic adenoma and mucoepidermoid carcinomaFascin overexpression promotes neoplastic progression in oral squamous cell carcinoma.Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastasesFascin-1, ezrin and paxillin contribute to the malignant progression and are predictors of clinical prognosis in laryngeal squamous cell carcinoma.Fascin promotes the motility and invasiveness of pancreatic cancer cells.Gefitinib-mediated reactive oxygen specie (ROS) instigates mitochondrial dysfunction and drug resistance in lung cancer cells.Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells.Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin
P2860
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P2860
Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Roles of fascin in human carci ...... ospects for a novel biomarker?
@ast
Roles of fascin in human carci ...... ospects for a novel biomarker?
@en
Roles of fascin in human carci ...... ospects for a novel biomarker?
@nl
type
label
Roles of fascin in human carci ...... ospects for a novel biomarker?
@ast
Roles of fascin in human carci ...... ospects for a novel biomarker?
@en
Roles of fascin in human carci ...... ospects for a novel biomarker?
@nl
prefLabel
Roles of fascin in human carci ...... ospects for a novel biomarker?
@ast
Roles of fascin in human carci ...... ospects for a novel biomarker?
@en
Roles of fascin in human carci ...... ospects for a novel biomarker?
@nl
P3181
P1476
Roles of fascin in human carci ...... ospects for a novel biomarker?
@en
P2093
Marek Skacel
Yosuke Hashimoto
P304
P3181
P356
10.1016/J.BIOCEL.2005.05.004
P407
P577
2005-09-01T00:00:00Z