Integrin-linked kinase is an adaptor with essential functions during mouse development
about
ILK: a pseudokinase in the center stage of cell-matrix adhesion and signalingMolecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell AdhesionStructural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinaseTitin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-lineMutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in miceStabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic responsePhactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activityRequirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesisIntegrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylationRegulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesPINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1.Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathyPINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alphaThe function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healingILK induces cardiomyogenesis in the human heart.Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction.A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.ILK mediates the effects of strain on intestinal epithelial wound closureA central multifunctional role of integrin-linked kinase at muscle attachment sites.Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex.Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progenyIntegrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.The sarcomeric Z-disc and Z-discopathies.Expression of focal adhesion proteins in the developing rat kidney.ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activationIdentification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survivalActopaxin (α-parvin) phosphorylation is required for matrix degradation and cancer cell invasionCharacterization of nuclear localization signal in the N terminus of integrin-linked kinase-associated phosphatase (ILKAP) and its essential role in the down-regulation of RSK2 protein signalingThe transcriptomic architecture of mouse Sertoli cell clone embryos reveals temporal–spatial-specific reprogramming.Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease.Focal adhesion complex proteins in epidermis and squamous cell carcinoma.A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease.Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout miceOsteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption.Extracellular matrix receptors in branched organsHow integrins control mammary epithelial differentiation: a possible role for the ILK-PINCH-Parvin complex.
P2860
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P2860
Integrin-linked kinase is an adaptor with essential functions during mouse development
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Integrin-linked kinase is an adaptor with essential functions during mouse development
@ast
Integrin-linked kinase is an adaptor with essential functions during mouse development
@en
Integrin-linked kinase is an adaptor with essential functions during mouse development
@nl
type
label
Integrin-linked kinase is an adaptor with essential functions during mouse development
@ast
Integrin-linked kinase is an adaptor with essential functions during mouse development
@en
Integrin-linked kinase is an adaptor with essential functions during mouse development
@nl
prefLabel
Integrin-linked kinase is an adaptor with essential functions during mouse development
@ast
Integrin-linked kinase is an adaptor with essential functions during mouse development
@en
Integrin-linked kinase is an adaptor with essential functions during mouse development
@nl
P2093
P921
P3181
P356
P1433
P1476
Integrin-linked kinase is an adaptor with essential functions during mouse development
@en
P2093
Anika Lange
Kirsi Sainio
Madis Jakobson
Sara A Wickström
P2888
P304
P3181
P356
10.1038/NATURE08468
P407
P577
2009-10-15T00:00:00Z
P5875
P6179
1044725358