BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses - Wikidata - awgldk - TriplyDB

BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses

BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses

http://www.wikidata.org/entity/Q28264207

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Human Oncogenic Herpesvirus and Post-translational Modifications - Phosphorylation and SUMOylation Proteomic approaches to uncovering virus-host protein interactions during the progression of viral infection Integrating Inflammasome Signaling in Sexually Transmitted Infections KSHV Entry and Trafficking in Target Cells-Hijacking of Cell Signal Pathways, Actin and Membrane Dynamics Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus.Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses.Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes.Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.The Emerging Roles of STING in Bacterial Infections.Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types.The expanding regulatory network of STING-mediated signaling.Discriminating self from non-self in nucleic acid sensing.Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease.DNA Oncogenic Virus-Induced Oxidative Stress, Genomic Damage, and Aberrant Epigenetic Alterations Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability.Kaposi sarcoma herpesvirus pathogenesis.DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.Role of Pattern Recognition Receptors in KSHV Infection.Nuclear-resident RIG-I senses viral replication inducing antiviral immunity Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16 Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis

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BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses

http://www.wikidata.org/entity/Q28264207

description

2015 nî lūn-bûn

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2015 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2015年の論文

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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BRCA1 Regulates IFI16 Mediated ...... ome and Interferon-β Responses

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Dipanjan Dutta

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Jawed Iqbal

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Karen E Johnson

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Leela Chikoti

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Mairaj Ahmed Ansari

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Mohanan Valiya Veettil

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Sujoy Dutta

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A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

IFI16 is an innate immune sensor for intracellular DNA

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Keeping it quiet: chromatin control of gammaherpesvirus latency

The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

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