The nuclear RNA surveillance machinery: the link between ncRNAs and genome structure in budding yeast?
about
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substratesTri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicingAir2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activationInhibition of polyadenylation reduces inflammatory gene inductionThe C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturationExecution of the meiotic noncoding RNA expression program and the onset of gametogenesis in yeast require the conserved exosome subunit Rrp6A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcriptsCcr4-Not complex: the control freak of eukaryotic cellsThe interplay of Hfq, poly(A) polymerase I and exoribonucleases at the 3' ends of RNAs resulting from Rho-independent termination: A tentative modelStructural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillanceActivities of human RRP6 and structure of the human RRP6 catalytic domainR-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity.The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex.SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae.RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complexRNA turnover and chromatin-dependent gene silencingQuantification of protein group coherence and pathway assignment using functional association.Distinct roles of non-canonical poly(A) polymerases in RNA metabolism.The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome.A local role for the small ribosomal subunit primary binder rpS5 in final 18S rRNA processing in yeast.Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Polyadenylation and degradation of incomplete RNA polymerase I transcripts in mammalian cells.Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4The exozyme model: a continuum of functionally distinct complexes.Identification and analysis of the RNA degrading complexes and machinery of Giardia lamblia using an in silico approach.A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation.Chromatin remodeling around nucleosome-free regions leads to repression of noncoding RNA transcription.Specificity factors in cytoplasmic polyadenylationThe mitochondrial RNA landscape of Saccharomyces cerevisiaeStructural components and architectures of RNA exosomesDistinct RNA degradation pathways and 3' extensions of yeast non-coding RNA speciesCoupling and coordination in gene expression processes with pre-mRNA splicing.Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs.The poly(A)-dependent degradation pathway of rpsO mRNA is primarily mediated by RNase R.A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.Virus-mediated mRNA decay by hyperadenylation.Life without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae.An mRNA-derived noncoding RNA targets and regulates the ribosome.
P2860
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P2860
The nuclear RNA surveillance machinery: the link between ncRNAs and genome structure in budding yeast?
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The nuclear RNA surveillance m ...... me structure in budding yeast?
@ast
The nuclear RNA surveillance m ...... me structure in budding yeast?
@en
The nuclear RNA surveillance m ...... me structure in budding yeast?
@nl
type
label
The nuclear RNA surveillance m ...... me structure in budding yeast?
@ast
The nuclear RNA surveillance m ...... me structure in budding yeast?
@en
The nuclear RNA surveillance m ...... me structure in budding yeast?
@nl
prefLabel
The nuclear RNA surveillance m ...... me structure in budding yeast?
@ast
The nuclear RNA surveillance m ...... me structure in budding yeast?
@en
The nuclear RNA surveillance m ...... me structure in budding yeast?
@nl
P1476
The nuclear RNA surveillance m ...... me structure in budding yeast?
@en
P304
P356
10.1016/J.BBAGRM.2007.12.008
P407
P577
2008-04-01T00:00:00Z