Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations
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Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC StudyEffects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretionThe role of melatonin in diabetes: therapeutic implicationsIncreased Insulin following an Oral Glucose Load, Genetic Variation near the Melatonin Receptor MTNR1B, but No Biochemical Evidence of Endothelial Dysfunction in Young Asian Men and WomenGenome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility lociFasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study.MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai.Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjectsVariants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the ChineseSystematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groupsA common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals.Circadian clocks and metabolism.MTNR1B Genetic Variability Is Associated with Gestational Diabetes in Czech Women.Relationship between melatonin receptor 1B and insulin receptor substrate 1 polymorphisms with gestational diabetes mellitus: a systematic review and meta-analysis.Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult populationAssociation of genetic variants of melatonin receptor 1B with gestational plasma glucose level and risk of glucose intolerance in pregnant Chinese women.A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulationCase-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.Large scale meta-analyses of fasting plasma glucose raising variants in GCK, GCKR, MTNR1B and G6PC2 and their impacts on type 2 diabetes mellitus risk.A low frequency variant within the GWAS locus of MTNR1B affects fasting glucose concentrations: genetic risk is modulated by obesityA common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesityGenetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.Genetic modifiers of response to glucose-insulin-potassium (GIK) infusion in acute coronary syndromes and associations with clinical outcomes in the IMMEDIATE trial.Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in miceGenetic determinants of cardiometabolic risk: a proposed model for phenotype association and interaction.Combined genome-wide linkage and association analyses of fasting glucose level in healthy twins and families of KoreaMelatonin pathway genes and breast cancer risk among Chinese women.Polymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer riskEvaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents.Glucose metabolism gene variants modulate the risk of pancreatic cancer.Genetic variants in MTNR1B affecting insulin secretion.Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.Ethnic differences in genetic predisposition to hypertension.Meta-analyses of the association of G6PC2 allele variants with elevated fasting glucose and type 2 diabetes.The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.Relevant associations of the glucokinase regulatory protein/glucokinase gene variation with TAG concentrations in a high-cardiovascular risk population: modulation by the Mediterranean diet.A multiple-ascending-dose study to evaluate safety, pharmacokinetics, and pharmacodynamics of a novel GPR40 agonist, TAK-875, in subjects with type 2 diabetes.Search for genetic determinants of sulfonylurea efficacy in type 2 diabetic patients from China.
P2860
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P2860
Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Common variants at the GCK, GC ...... ucose in two Asian populations
@ast
Common variants at the GCK, GC ...... ucose in two Asian populations
@en
Common variants at the GCK, GC ...... ucose in two Asian populations
@nl
type
label
Common variants at the GCK, GC ...... ucose in two Asian populations
@ast
Common variants at the GCK, GC ...... ucose in two Asian populations
@en
Common variants at the GCK, GC ...... ucose in two Asian populations
@nl
prefLabel
Common variants at the GCK, GC ...... ucose in two Asian populations
@ast
Common variants at the GCK, GC ...... ucose in two Asian populations
@en
Common variants at the GCK, GC ...... ucose in two Asian populations
@nl
P2093
P3181
P1433
P1476
Common variants at the GCK, GC ...... ucose in two Asian populations
@en
P2093
A de Silva
E Nakashima
F Takeuchi
K Yamamoto
M Serizawa
R Takayanagi
P2888
P304
P3181
P356
10.1007/S00125-009-1595-1
P407
P577
2009-11-25T00:00:00Z
P5875
P6179
1027597649