Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine
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Formation of mono- and bis-Michael adducts by the reaction of nucleophilic amino acids with hydroxymethylvinyl ketone, a reactive metabolite of 1,3-butadieneHydroxynonenal inactivates cathepsin B by forming Michael adducts with active site residues.Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids.Nitrated fatty acids: Endogenous anti-inflammatory signaling mediatorsReversible post-translational modification of proteins by nitrated fatty acids in vivo.Mass spectrometric evidence for the existence of distinct modifications of different proteins by 2(E),4(E)-decadienalRedox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy.Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Chemical probes for analysis of carbonylated proteins: a review.Inactivation of ethanol-inducible cytochrome P450 and other microsomal P450 isozymes by trans-4-hydroxy-2-nonenal, a major product of membrane lipid peroxidation.New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects.Comparative analysis of gene expression changes mediated by individual constituents of hemozoin.Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate.4-hydroxy-2-nonenal-modified glyceraldehyde-3-phosphate dehydrogenase is degraded by cathepsin G in rat neutrophils.4-Hydroperoxy-2-nonenal is not just an intermediate but a reactive molecule that covalently modifies proteins to generate unique intramolecular oxidation products.Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction.Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4.Application of the Hard and Soft, Acids and Bases (HSAB) theory to toxicant--target interactions.Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine.Declines in mitochondrial respiration during cardiac reperfusion: age-dependent inactivation of alpha-ketoglutarate dehydrogenaseImmunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytesMitochondrial adenine nucleotide translocase is modified oxidatively during aging.Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNEDelivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature.Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells.Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation.Crystal Structure of the Chloroplastic Oxoene Reductase ceQORH from Arabidopsis thalianaSubcellular Redox Targeting: Bridging in Vitro and in Vivo Chemical Biology.Murine hepatic aldehyde dehydrogenase 1a1 is a major contributor to oxidation of aldehydes formed by lipid peroxidation.Mass spectrometric characterization of protein modification by the products of nonenzymatic oxidation of linoleic acid.Biochemistry and pathology of radical-mediated protein oxidation.Stereochemical configuration of 4-hydroxy-2-nonenal-cysteine adducts and their stereoselective formation in a redox-regulated protein.Crystallization and molecular-replacement studies of the monoclonal antibody mAbR310 specific for the (R)-HNE-modified protein.Lipid peroxidation products and antioxidants in human disease.4-Hydroxy-2(E)-nonenal enantiomers: (S)-selective inactivation of glyceraldehyde-3-phosphate dehydrogenase and detoxification by rat glutathione S-transferase A4-4.Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein.Protection against photooxidative injury of tobacco leaves by 2-alkenal reductase. Detoxication of lipid peroxide-derived reactive carbonyls.
P2860
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P2860
Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine
description
1993 nî lūn-bûn
@nan
1993 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@ast
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@en
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@nl
type
label
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@ast
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@en
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@nl
prefLabel
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@ast
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@en
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@nl
P2093
P1476
Inactivation of glucose-6-phos ...... ation of an active-site lysine
@en
P2093
P304
P407
P577
1993-02-01T00:00:00Z