Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor
about
Actinomycin D enhances killing of cancer cells by immunotoxin RG7787 through activation of the extrinsic pathway of apoptosis.Influence of DPH1 and DPH5 Protein Variants on the Synthesis of Diphthamide, the Target of ADPRibosylating Toxins.Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing.A re-engineered immunotoxin shows promising preclinical activity in ovarian cancer.5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.Diphthamide affects selenoprotein expression: Diphthamide deficiency reduces selenocysteine incorporation, decreases selenite sensitivity and pre-disposes to oxidative stressImportance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
P2860
Q37281460-EF94708C-06A8-4B44-8E3F-700CFB62290FQ42293412-5E94FEFC-5354-40F7-8C05-4674278CC308Q46440057-95338C3C-00C3-4484-88B0-925DDEF215CEQ47128416-7A510C5A-30FD-4337-BF22-0972A9C98298Q50063870-7353A9D0-8FCF-4A50-825C-AA3FBEF6C3FDQ57491820-76818C83-A7E3-4F01-9564-ED447A863A0AQ58601992-A17D4D6D-F430-4D78-A7F0-8A5EF3D76378
P2860
Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor
description
2015 nî lūn-bûn
@nan
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@ast
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@en
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@nl
type
label
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@ast
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@en
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@nl
prefLabel
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@ast
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@en
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@nl
P2093
P2860
P356
P1476
Loss of diphthamide pre-activa ...... itive to tumor necrosis factor
@en
P2093
Alexander K Haas
Ana Rita da Silva Mateus Seidl
Axel Ducret
Fabian Birzele
Gerhard Niederfellner
Ira Pastan
Michael Gerg
Ruediger Rueger
Sabine Kux van Geijtenbeek
Sebastian Stahl
P2860
P304
P356
10.1073/PNAS.1512863112
P407
P577
2015-08-25T00:00:00Z