2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products
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Rational and combinatorial tailoring of bioactive cyclic dipeptidesThe tRNA-dependent biosynthesis of modified cyclic dipeptidesLysobacter capsici AZ78 produces cyclo(L-Pro-L-Tyr), a 2,5-diketopiperazine with toxic activity against sporangia of Phytophthora infestans and Plasmopara viticolaDesign, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 InteractionThe Epipolythiodiketopiperazine Gene Cluster in Claviceps purpurea: Dysfunctional Cytochrome P450 Enzyme Prevents Formation of the Previously Unknown ClapurinesA new diketopiperazine derivative from a deep sea-derived Streptomyces sp. SCSIO 04496.Enantioselective Synthesis of (-)-Acetylapoaranotin.Proline-Based Cyclic Dipeptides from Korean Fermented Vegetable Kimchi and from Leuconostoc mesenteroides LBP-K06 Have Activities against Multidrug-Resistant Bacteria.Cyclo(valine-valine) inhibits Vibrio cholerae virulence gene expression.Epidithiodiketopiperazines: Strain-Promoted Thiol-Mediated Cellular Uptake at the Highest Tension.2,5-diketopiperazines in food and beverages: Taste and bioactivity.An update on 2,5-diketopiperazines from marine organisms.Spontaneous cyclization of polypeptides with a penultimate Asp, Asn or isoAsp at the N-terminus and implications for cleavage by aminopeptidase.Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine unitsA one-pot multicomponent coupling/cyclization for natural product herbicide (±)-thaxtomin A.Diversity and bioprospecting of culturable actinomycetes from marine sediment of the Yellow Sea, China.A benzotriazole-mediated route to protected marine-derived hetero-2,5-diketopiperazines containing proline.A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffoldsTricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.Purification and synergistic antibacterial activity of arginine derived cyclic dipeptides, from Achromobacter sp. associated with a rhabditid entomopathogenic nematode against major clinically relevant biofilm forming wound bacteria.Biofocussed chemoprospecting: An efficient approach for drug discovery.Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haConcise Synthesis of Tetrazole-keto-piperazines by Two Consecutive Ugi Reactions.Genomics and physiology of a marine flavobacterium encoding a proteorhodopsin and a xanthorhodopsin-like protein.General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.Privileged scaffolds in synthesis: 2,5-piperazinediones as templates for the preparation of structurally diverse heterocycles.Developments around the bioactive diketopiperazines: a patent review.Anticancer and antifungal compounds from Aspergillus, Penicillium and other filamentous fungi.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis.The role of intramolecular self-destruction of reactive metabolic intermediates in determining toxicity.The Antiproliferative Effect of Cyclodipeptides from Pseudomonas aeruginosa PAO1 on HeLa Cells Involves Inhibition of Phosphorylation of Akt and S6k Kinases.Lactococcus lactis KR-050L inhibit IL-6/STAT3 activation.Two novel cyclic hexapeptides from the genetically engineered Actinosynnema pretiosum.Novel propanamide analogue and antiproliferative diketopiperazines from mangrove Streptomyces sp. Q24.Three new 2,5-diketopiperazines from the fish intestinal Streptomyces sp. MNU FJ-36.Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction.Cyclo(D-Tyr-D-Phe): a new antibacterial, anticancer, and antioxidant cyclic dipeptide from Bacillus sp. N strain associated with a rhabditid entomopathogenic nematode.New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039.
P2860
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P2860
2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@ast
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@en
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@nl
type
label
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@ast
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@en
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@nl
prefLabel
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@ast
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@en
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@nl
P3181
P356
P1433
P1476
2,5-Diketopiperazines: synthes ...... and bioactive natural products
@en
P2093
Alan D Borthwick
P304
P3181
P356
10.1021/CR200398Y
P407
P577
2012-07-11T00:00:00Z