The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression

The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression

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http://www.wikidata.org/entity/Q28266918

Q28266918

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The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability Recent progress in the development of polysaccharide conjugates of docetaxel and paclitaxel The roles of hyaluronan/RHAMM/CD44 and their respective interactions along the insidious pathways of fibrosarcoma progression RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility Small activating RNA restores the activity of the tumor suppressor HIC-1 on breast cancer RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease.Prestige centrality-based functional outlier detection in gene expression analysis.Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells.Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer.Prognostic impact of CD168 expression in gastric cancer.Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells.Apical oxidative hyaluronan degradation stimulates airway ciliary beating via RHAMM and RON.Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival.Mechanism of MTA1 protein overexpression-linked invasion: MTA1 regulation of hyaluronan-mediated motility receptor (HMMR) expression and function.EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer.Immune responses to RHAMM in patients with acute myeloid leukemia after chemotherapy and allogeneic stem cell transplantation Bub1 is required for maintaining cancer stem cells in breast cancer cell lines Upregulation of hyaluronan-mediated motility receptor in hepatocellular carcinoma predicts poor survival.RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia.Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model.Improved biochemical strategies for targeted delivery of taxoids Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment Two-marker protein profile predicts poor prognosis in patients with early rectal cancer RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation Hyaluronan and hyaluronidase in genitourinary tumors.Prognostic significance of CD168 overexpression in colorectal cancer Hyaluronic acid promotes angiogenesis by inducing RHAMM-TGFβ receptor interaction via CD44-PKCδ.Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development.Hyaluronan-CD44 interaction promotes c-Jun signaling and miRNA21 expression leading to Bcl-2 expression and chemoresistance in breast cancer cells.Hyaluronan and RHAMM in wound repair and the "cancerization" of stromal tissues.The hyaluronan receptor for endocytosis mediates hyaluronan-dependent signal transduction via extracellular signal-regulated kinases.RB Loss Promotes Prostate Cancer Metastasis.Receptor for Hyaluronic Acid-Mediated Motility is Associated with Poor Survival in Pancreatic Ductal Adenocarcinoma Carcinoma Cell Hyaluronan as a "Portable" Cancerized Prometastatic Microenvironment.Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.Synergistic effect of interleukin-6 and hyaluronic acid on cell migration and ERK activation in human keratinocytes.The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

P2860

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P2860

The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression

Item

http://www.wikidata.org/entity/Q28266918

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1998 nî lūn-bûn

@nan

1998 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի մարտին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu