Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases - Wikidata - awgldk - TriplyDB

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

http://www.wikidata.org/entity/Q28267092

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Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes Defective T cell receptor-mediated signal transduction in memory CD4 T lymphocytes exposed to superantigen or anti-T cell receptor antibodies The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase Systematic approaches to identify E3 ligase substrates The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte The Cbl interactome and its functions Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323 The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation The Syk family of protein tyrosine kinases in T-cell activation and development A dynamic view of domain-motif interactions.Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding.Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl.Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.Signaling pathways in phagocytosis.c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.Tyrosines in the carboxyl terminus regulate Syk kinase activity and function Cbl: many adaptations to regulate protein tyrosine kinases.Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.Beyond the RING: CBL proteins as multivalent adapters.Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways.A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling Superantigen-induced CD4 memory T cell anergy. I. Staphylococcal enterotoxin B induces Fyn-mediated negative signaling Anergy in CD4 memory T lymphocytes. II. Abrogation of TCR-induced formation of membrane signaling complexes Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome.Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy against Waldenström Macroglobulinemia.c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells Syk and pTyr'd: Signaling through the B cell antigen receptor

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P2860

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

http://www.wikidata.org/entity/Q28267092

description

1998 nî lūn-bûn

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1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1998 թվականի ապրիլին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年论文

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Coordinated regulation of the ...... y Fyn and Syk tyrosine kinases

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Coordinated regulation of the ...... y Fyn and Syk tyrosine kinases

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Coordinated regulation of the ...... y Fyn and Syk tyrosine kinases

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Journal of Biological Chemistry

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Coordinated regulation of the ...... y Fyn and Syk tyrosine kinases

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A Altman

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M Deckert

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P2860

The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner

Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif

Activation-modulated association of 14-3-3 proteins with Cbl in T cells

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

The PTB domain: a new protein module implicated in signal transduction

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

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phosphorylation