Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications
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Prospecting for novel plant-derived molecules of Rauvolfia serpentina as inhibitors of Aldose Reductase, a potent drug target for diabetes and its complicationsHuman aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolismFundamental roles of reactive oxygen species and protective mechanisms in the female reproductive systemProtein Modifications as Manifestations of Hyperglycemic Glucotoxicity in Diabetes and Its ComplicationsHyperglycemic Stress and Carbon Stress in Diabetic GlucotoxicityRoles of Pyruvate, NADH, and Mitochondrial Complex I in Redox Balance and Imbalance in β Cell Function and DysfunctionQuantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductaseStructure of 2-oxo-3-deoxygalactonate kinase fromKlebsiella pneumoniaeStructure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPHStructural and kinetic modifications of aldose reductase by S-nitrosothiolsIdentification of Novel Aldose Reductase Inhibitors from Spices: A Molecular Docking and Simulation StudyPathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress.Aldose reductase inhibition ameliorates the detrimental effect of estrogen replacement therapy on neuropathology in diabetic rats subjected to transient forebrain ischemia.Aldose reductase-deficient mice develop nephrogenic diabetes insipidus.Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat.Nox-4 deletion reduces oxidative stress and injury by PKC-α-associated mechanisms in diabetic nephropathy.Involvement of the TAGE-RAGE system in non-alcoholic steatohepatitis: Novel treatment strategiesHuman and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde.Bioactive fraction of Saraca indica prevents diabetes induced cataractogenesis: An aldose reductase inhibitory activity.Aldose reductase gene is associated with diabetic macroangiopathy in Japanese Type 2 diabetic patients.Electrostatic complementarity in an aldose reductase complex from ultra-high-resolution crystallography and first-principles calculationsInhibition of aldose reductase activates hepatic peroxisome proliferator-activated receptor-α and ameliorates hepatosteatosis in diabetic db/db mice.Aldose reductase expression as a risk factor for cataractOsmolarity and glucose differentially regulate aldose reductase activity in cultured mouse podocytes.Early diabetic neuropathy: triggers and mechanisms.Protective Pleiotropic Effect of Flavonoids on NAD⁺ Levels in Endothelial Cells Exposed to High Glucose.Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships.Aldose reductase, oxidative stress, and diabetic mellitus.The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect.Aldose reductase inhibitory activity of compounds from Zea mays LMetabolomic Profiling of Post-Mortem Brain Reveals Changes in Amino Acid and Glucose Metabolism in Mental Illness Compared with ControlsOverexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death.Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.Cellular signaling and potential new treatment targets in diabetic retinopathy.Crystallization and preliminary X-ray analysis of a rat aldose reductase-like protein (AKR1B14).Beneficial Effect of 7-O-Galloyl-D-sedoheptulose, a Polyphenol Isolated from Corni Fructus, against Diabetes-Induced Alterations in Kidney and Adipose Tissue of Type 2 Diabetic db/db MiceRedox imbalance and mitochondrial abnormalities in the diabetic lung.Revisiting "Vegetables" to combat modern epidemic of imbalanced glucose homeostasisNovel insights into the mechanisms whereby isoflavones protect against fatty liver disease.Expression of AKR1C3 and CNN3 as markers for detection of lymph node metastases in colorectal cancer.
P2860
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P2860
Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Aldose reductase in glucose to ...... tion of diabetic complications
@ast
Aldose reductase in glucose to ...... tion of diabetic complications
@en
Aldose reductase in glucose to ...... tion of diabetic complications
@nl
type
label
Aldose reductase in glucose to ...... tion of diabetic complications
@ast
Aldose reductase in glucose to ...... tion of diabetic complications
@en
Aldose reductase in glucose to ...... tion of diabetic complications
@nl
prefLabel
Aldose reductase in glucose to ...... tion of diabetic complications
@ast
Aldose reductase in glucose to ...... tion of diabetic complications
@en
Aldose reductase in glucose to ...... tion of diabetic complications
@nl
P3181
P1476
Aldose reductase in glucose to ...... tion of diabetic complications
@en
P2093
C Yabe-Nishimura
P3181
P407
P577
1998-03-01T00:00:00Z