Allosteric modulation of the cannabinoid CB1 receptor - Wikidata - awgldk - TriplyDB

Allosteric modulation of the cannabinoid CB1 receptor

Allosteric modulation of the cannabinoid CB1 receptor

http://www.wikidata.org/entity/Q28268355

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Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporter PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats Cannabinoid receptor type-1: breaking the dogmas The Endocannabinoid System as a Therapeutic Target in Glaucoma Minireview: From the bench, toward the clinic: therapeutic opportunities for cannabinoid receptor modulation Gaddum Memorial Lecture 2014: receptors as an evolving concept: from switches to biased microprocessors Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments.Presynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂ The pharmacology of cannabinoid receptors and their ligands: an overview A unified view of "how allostery works"Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development Allosteric modulation of metabotropic glutamate receptors.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Cannabinoid CB1 receptor immunoreactivity in the prefrontal cortex: Comparison of schizophrenia and major depressive disorder.Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors.Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors.Insect repellents: modulators of mosquito odorant receptor activity.High-resolution crystal structure of the human CB1 cannabinoid receptor.In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569 Interactions of Cannabinoids With Biochemical Substrates CB1 allosteric modulator Org27569 is an antagonist/inverse agonist of ERK1/2 signaling.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia Effects of the cannabinoid CB₁ receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?Psychopharmacology of the endocannabinoids: far beyond anandamide.Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).Reciprocal alterations in cortical cannabinoid receptor 1 binding relative to protein immunoreactivity and transcript levels in schizophrenia.Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats The hinge region of human thyroid-stimulating hormone (TSH) receptor operates as a tunable switch between hormone binding and receptor activation.Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1).Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction.A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.

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P2860

Allosteric modulation of the cannabinoid CB1 receptor

http://www.wikidata.org/entity/Q28268355

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2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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label

Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Allosteric modulation of the cannabinoid CB1 receptor

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Molecular Pharmacology

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Allosteric modulation of the cannabinoid CB1 receptor

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Adèle McLean

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Gemma L Baillie

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Gillian Goodwin

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Glenn Walker

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Julia Marrs

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Lesley A Stevenson

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Lorraine McIntosh

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Martin R Price

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Morag Easson

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Paul Westwood

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1394719

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10.1124/MOL.105.016162

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5

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68

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Roger G. Pertwee

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Arthur Christopoulos

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7647831

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16113085

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cannabinoid receptor