FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway

FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway

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http://www.wikidata.org/entity/Q28269431
Insights into Fanconi Anaemia from the structure of human FANCEThe role of the Fanconi anemia network in the response to DNA replication stress.The genetic and biochemical basis of FANCD2 monoubiquitinationGenetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc)The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly.RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation.Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy.The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2.The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic SarcomasModularized functions of the Fanconi anemia core complex.Towards a molecular understanding of the fanconi anemia core complexMutations in Fanconi anemia genes and the risk of esophageal cancer.
P2860

FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway

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http://www.wikidata.org/entity/Q28269431
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2005 nî lūn-bûn
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2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年论文
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FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@ast
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@en
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@nl
type
label
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@ast
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@en
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@nl
prefLabel
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@ast
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@en
FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@nl
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P1476
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P2860
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P31
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FANCC, FANCE, and FANCD2 form ...... ia DNA damage response pathway
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921