Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1 - Wikidata - awgldk - TriplyDB

Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1

Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1

http://www.wikidata.org/entity/Q28270318

about

Arginine methyltransferases as novel therapeutic targets for breast cancer Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition.Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site Histone methylation modifiers in cellular signaling pathways Readers of histone methylarginine marks.Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function.Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Chemical biology of protein arginine modifications in epigenetic regulation Influences of the Gut Microbiota on DNA Methylation and Histone Modification.A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase.Protein Arginine Methylation and Citrullination in Epigenetic Regulation Small Molecule Inhibitors of Protein Arginine Methyltransferases.Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness.Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors.Cloning, expression, purification and preliminary X-ray crystallographic analysis of mouse protein arginine methyltransferase 7.Nucleic acid oxidation in DNA damage repair and epigenetics Protein arginine methylation of non-histone proteins and its role in diseases.Role of PRMTs in cancer: Could minor isoforms be leaving a mark?Prmt7 is dispensable in tissue culture models for adipogenic differentiation.POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies Protein arginine methylation/demethylation and cancer.Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.Discovery of a Dual PRMT5-PRMT7 Inhibitor.Protein Arginine Methyltransferase Product Specificity Is Mediated by Distinct Active-site Architectures.Altered expression of an RBP-associated arginine methyltransferase 7 in Leishmania major affects parasite infection.Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.Loss of the arginine methyltranserase PRMT7 causes syndromic intellectual disability with microcephaly and brachydactyly.Gene expression profiling identifies different sub-types of retinoblastoma.Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases.Caenorhabditis elegans PRMT-7 and PRMT-9 Are Evolutionarily Conserved Protein Arginine Methyltransferases with Distinct Substrate Specificities.contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with and

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P2860

Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1

http://www.wikidata.org/entity/Q28270318

description

2012 nî lūn-bûn

@nan

2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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type

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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prefLabel

Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

@en

Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

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JBC.M112.378281

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Journal of Biological Chemistry

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Protein arginine methyltransfe ...... catalytic subunit gene, POLD1

@en

P2093

Anthony N Imbalzano

http://www.w3.org/2001/XMLSchema#string

Li Wang

http://www.w3.org/2001/XMLSchema#string

Saïd Sif

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Sookil Tae

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Vrajesh Karkhanis

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Yu-Jie Hu

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P2860

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation

PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine

PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad

Regulation of transcription by a protein methyltransferase

Regulation of histone methylation by demethylimination and demethylation

Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene

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scholarly article

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3573614

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10.1074/JBC.M112.378281

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35

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287

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2012-08-24T00:00:00Z

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22761421

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3436169

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