Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC - Wikidata - awgldk - TriplyDB

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

http://www.wikidata.org/entity/Q28271418

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Characterization of Diaphanous-related formin FMNL2 in human tissues Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration Cell polarity signaling in the plasticity of cancer cell invasiveness Filopodia and adhesion in cancer cell motility Regulation of ROCK activity in cancer RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1.The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.Genome-wide association analysis of ischemic stroke in young adults.RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion.A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinement Toward understanding RhoGTPase specificity: structure, function and local activation.RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Polarity gene alterations in pure invasive micropapillary carcinomas of the breast Cellular control of cortical actin nucleation.Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.Systems genetics of the lateral septal nucleus in mouse: heritability, genetic control, and covariation with behavioral and morphological traits.Dia-interacting protein (DIP) imposes migratory plasticity in mDia2-dependent tumor cells in three-dimensional matrices.Overexpression of Ras homologous C (RhoC) induces malignant transformation of hepatocytes in vitro and in nude mouse xenografts.An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex.Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.A specific FMNL2 isoform is up-regulated in invasive cells ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions.The MLK-related kinase (MRK) is a novel RhoC effector that mediates lysophosphatidic acid (LPA)-stimulated tumor cell invasion FMNL2/FMNL3 formins are linked with oncogenic pathways and predict melanoma outcome.Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment.Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer.Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking.Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction.Emerging molecular targets in melanoma invasion and metastasis.RhoA, RhoB and RhoC have different roles in cancer cell migration.Pharmacological inhibition of actin assembly to target tumor cell motility.

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P2860

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

http://www.wikidata.org/entity/Q28271418

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@ast

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@en

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@nl

type

label

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@ast

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@en

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@nl

prefLabel

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@ast

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@en

Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@nl

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Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC

@en

P2093

J W Copeland

http://www.w3.org/2001/XMLSchema#string

T M Kitzing

http://www.w3.org/2001/XMLSchema#string

Y Wang

http://www.w3.org/2001/XMLSchema#string

P2860

PRK1 is targeted to endosomes by the small GTPase, RhoB

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

An integrated genomic analysis of human glioblastoma multiforme

Cell motility through plasma membrane blebbing

Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function.

Genomic analysis of metastasis reveals an essential role for RhoC

Staying in shape with formins

Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

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2441-2448

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scholarly article

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3829737

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10.1038/ONC.2009.515

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16

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29

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2010-01-25T00:00:00Z

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41139517

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1004057156

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20101212

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