Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system
about
Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesMultiple Targeting Approaches on Histamine H3 Receptor AntagonistsComputational methods in drug discoveryHistamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenatesAnticonvulsant effects of isomeric nonimidazole histamine H3 receptor antagonistsZebrafish: An in vivo model for the study of neurological diseases.Drugs for sleep disorders: mechanisms and therapeutic prospectsAnxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H₃ receptor antagonist ST-1283.The H3 antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteersAlzheimer's disease and age-related memory decline (preclinical)Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [¹¹C]GSK189254 in anesthetized baboon.Evaluation of Thioperamide Effects Using Rat's Trachea Model.Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.Histamine H1 receptor blockade predominantly impairs sensory processes in human sensorimotor performance.Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM miceApproaches to measuring the effects of wake-promoting drugs: a focus on cognitive function.Altered expression of histamine signaling genes in autism spectrum disorder.The Synergistic Enhancing-Memory Effect of Donepezil and S 38093 (a Histamine H3 Antagonist) Is Mediated by Increased Neural Activity in the Septo-hippocampal Circuitry in Middle-Aged Mice.The histamine H3 receptor antagonist thioperamide rescues circadian rhythm and memory function in experimental parkinsonism.Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease.H3 receptor antagonism enhances NCAM PSA-mediated plasticity and improves memory consolidation in odor discrimination and delayed match-to-position paradigms.The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats.High levels of histidine decarboxylase in the striatum of mice and rats.Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists.Atomoxetine increases histamine release and improves learning deficits in an animal model of attention-deficit hyperactivity disorder: the spontaneously hypertensive rat.Histamine H1-receptor blockade in humans affects psychomotor performance but not memory.Effects of lisdexamfetamine alone and in combination with s-citalopram on acetylcholine and histamine efflux in the rat pre-frontal cortex and ventral hippocampus.Antihistamine induced blood oxygenation level dependent response changes related to visual processes during sensori-motor performance.Anticonvulsant and reproductive toxicological studies of the imidazole-based histamine H3R antagonist 2-18 in mice.The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats.Additive effects of a cholinesterase inhibitor and a histamine inverse agonist on scopolamine deficits in humans.JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder.
P2860
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P2860
Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Selective histamine H3 recepto ...... of the central nervous system
@ast
Selective histamine H3 recepto ...... of the central nervous system
@en
Selective histamine H3 recepto ...... of the central nervous system
@nl
type
label
Selective histamine H3 recepto ...... of the central nervous system
@ast
Selective histamine H3 recepto ...... of the central nervous system
@en
Selective histamine H3 recepto ...... of the central nervous system
@nl
prefLabel
Selective histamine H3 recepto ...... of the central nervous system
@ast
Selective histamine H3 recepto ...... of the central nervous system
@en
Selective histamine H3 recepto ...... of the central nervous system
@nl
P3181
P1476
Selective histamine H3 recepto ...... of the central nervous system
@en
P2093
D L Nelson
J M Witkin
P3181
P356
10.1016/J.PHARMTHERA.2004.05.001
P407
P577
2004-07-01T00:00:00Z