Nonmevalonate terpene biosynthesis enzymes as antiinfective drug targets: substrate synthesis and high-throughput screening methods
about
The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discoveryCharacterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discoveryInhibitors of the herbicidal target IspD: allosteric site bindingPseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspDIsoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasitesIdentifying essential genes in bacterial metabolic networks with machine learning methodsSynthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspFBiochemistry of the non-mevalonate isoprenoid pathway.In search of new herbicidal inhibitors of the non-mevalonate pathway.Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using (1)H-(31)P-(31)P correlation NMR spectroscopy.Development of an image-based screening system for inhibitors of the plastidial MEP pathway and of protein geranylgeranylation.IspG-catalyzed positional isotopic exchange in methylerythritol cyclodiphosphate of the deoxyxylulose phosphate pathway: mechanistic implications.Synthesis and evaluation of stable substrate analogs as potential modulators of cyclodiphosphate synthase IspF.2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activityMetabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene.Biosynthesis of isoprenoids: studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase.Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.Aryl Bis-Sulfonamide Inhibitors of IspF fromArabidopsis thalianaandPlasmodium falciparum
P2860
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P2860
Nonmevalonate terpene biosynthesis enzymes as antiinfective drug targets: substrate synthesis and high-throughput screening methods
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@ast
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@en
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@nl
type
label
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@ast
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@en
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@nl
prefLabel
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@ast
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@en
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@nl
P2093
P356
P1476
Nonmevalonate terpene biosynth ...... h-throughput screening methods
@en
P2093
Elena Ostrozhenkova
Felix Rohdich
Johannes Kaiser
Markus Fischer
Victoria Illarionova
Wolfgang Eisenreich
P304
P356
10.1021/JO061466O
P407
P577
2006-11-10T00:00:00Z