Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein
about
Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering.The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.Multitasking of Ig-alpha and Ig-beta to regulate B cell antigen receptor function.Generation of heavy-chain-only antibodies in mice.Development of B cells expressing surface immunoglobulin molecules that lack V(D)J-encoded determinants in the avian embryo bursa of fabriciusCore fucosylation of μ heavy chains regulates assembly and intracellular signaling of precursor B cell receptors.Differential effect of an Ig mu transgene on development of pre-B cells in fetal and adult SCID mice.A conformation-induced oligomerization model for B cell receptor microclustering and signalingSurrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition.Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion.ITAM-mediated tonic signalling through pre-BCR and BCR complexes.The variable, C(H)1, C(H)2 and C(H)3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice.
P2860
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P2860
Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Pre-B-cell development in the ...... a heavy-chain disease protein
@ast
Pre-B-cell development in the ...... a heavy-chain disease protein
@en
Pre-B-cell development in the ...... a heavy-chain disease protein
@nl
type
label
Pre-B-cell development in the ...... a heavy-chain disease protein
@ast
Pre-B-cell development in the ...... a heavy-chain disease protein
@en
Pre-B-cell development in the ...... a heavy-chain disease protein
@nl
prefLabel
Pre-B-cell development in the ...... a heavy-chain disease protein
@ast
Pre-B-cell development in the ...... a heavy-chain disease protein
@en
Pre-B-cell development in the ...... a heavy-chain disease protein
@nl
P2093
P1433
P1476
Pre-B-cell development in the ...... a heavy-chain disease protein
@en
P2093
P304
P356
10.1016/S0960-9822(95)00230-2
P407
P577
1995-10-01T00:00:00Z