Human Trop-2 is a tumor-associated calcium signal transducer
about
Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophyCurrent Stem Cell Biomarkers and Their Functional Mechanisms in Prostate CancerCharacteristics of corneal dystrophies: a review from clinical, histological and genetic perspectivesTrop-2 is a determinant of breast cancer survivalRegulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signalingIdentification and characterization of a novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy.Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.Discovery of novel tumor markers of pancreatic cancer using global gene expression technology.Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling.A novel TACSTD2 mutation identified in two Chinese brothers with gelatinous drop-like corneal dystrophy.Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways.Identification of novel targets for breast cancer by exploring gene switches on a genome scale.Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway.A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.Trop-2 protein overexpression is an independent marker for predicting disease recurrence in endometrioid endometrial carcinoma.A novel human Fab antibody for Trop2 inhibits breast cancer growth in vitro and in vivo.Overexpression of TROP2 predicts poor prognosis of patients with cervical cancer and promotes the proliferation and invasion of cervical cancer cells by regulating ERK signaling pathway.Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody.TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.Prognostic value of TROP2 in human nasopharyngeal carcinoma.Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule.High expression of TROP2 correlates with poor prognosis in pancreatic cancer.Impact of TROP2 expression on prognosis in solid tumors: A Systematic Review and Meta-analysisThe tumor-inhibitory effectiveness of a novel anti-Trop2 Fab conjugate in pancreatic cancer.Two novel mutations identified in two Chinese gelatinous drop-like corneal dystrophy families.Chemotherapy agents-induced immunoresistance in lung cancer cells could be reversed by trop-2 inhibition in vitro and in vivo by interaction with MAPK signaling pathway.Loss of TACSTD2 contributed to squamous cell carcinoma progression through attenuating TAp63-dependent apoptosis.Pretargeted molecular imaging and radioimmunotherapy.Trop2: from development to disease.Overexpression of trophoblast cell surface antigen 2 as an independent marker for a poor prognosis and as a potential therapeutic target in epithelial ovarian carcinoma.Expression of Trop2 cell surface glycoprotein in normal and tumor tissues: potential implications as a cancer therapeutic target.Regulatory roles of grass carp EpCAM in cell morphology, proliferation and migration.Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axisEstablishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development.Discrimination of benign and malignant thyroid nodules by molecular profiling.cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model.Cyclin D1 gene contains a cryptic promoter that is functional in human cancer cells.TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.Overexpression of TROP2 promotes proliferation and invasion of ovarian cancer cells.
P2860
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P2860
Human Trop-2 is a tumor-associated calcium signal transducer
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Human Trop-2 is a tumor-associated calcium signal transducer
@ast
Human Trop-2 is a tumor-associated calcium signal transducer
@en
Human Trop-2 is a tumor-associated calcium signal transducer
@nl
type
label
Human Trop-2 is a tumor-associated calcium signal transducer
@ast
Human Trop-2 is a tumor-associated calcium signal transducer
@en
Human Trop-2 is a tumor-associated calcium signal transducer
@nl
prefLabel
Human Trop-2 is a tumor-associated calcium signal transducer
@ast
Human Trop-2 is a tumor-associated calcium signal transducer
@en
Human Trop-2 is a tumor-associated calcium signal transducer
@nl
P2093
P2860
P3181
P1476
Human Trop-2 is a tumor-associated calcium signal transducer
@en
P2093
P2860
P304
P3181
P356
10.1002/(SICI)1097-0215(19980529)76:5<671::AID-IJC10>3.0.CO;2-7
P407
P577
1998-05-01T00:00:00Z