Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
about
The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotesThe NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in ArabidopsisNew drug target in protozoan parasites: the role of thioredoxin reductaseThe basics of thiols and cysteines in redox biology and chemistryStructure ofLeishmania majorcysteine synthaseLeishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activationDihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein CrystallographyIron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei : Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite InfectivityThe narrow active-site cleft of O-acetylserine sulfhydrylase from Leishmania donovani allows complex formation with serine acetyltransferases with a range of C-terminal sequencesInhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum ProliferationStructural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthaseCurrent challenges in treatment options for visceral leishmaniasis in India: a public health perspectivePentavalent antimonials: new perspectives for old drugsThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingLinking in vitro and in vivo survival of clinical Leishmania donovani strainsMitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activityStage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovaniThe Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulenceTrypanothione reductase: a target protein for a combined in vitro and in silico screening approachGenetic Manipulation of Leishmania donovani to Explore the Involvement of Argininosuccinate Synthase in Oxidative Stress ManagementIdentification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic TrypanosomatidsPolyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilitiesLC-MS metabolomics from study design to data-analysis - using a versatile pathogen as a test case.Proteomic analysis of Trypanosoma cruzi response to ionizing radiation stressQuiescin sulfhydryl oxidase from Trypanosoma brucei: catalytic activity and mechanism of a QSOX family member with a single thioredoxin domain.Genetic validation of Trypanosoma brucei glutathione synthetase as an essential enzyme.Leishmania subtilisin is a maturase for the trypanothione reductase system and contributes to disease pathology.Evaluation of Antitrypanosomal Dihydroquinolines for Hepatotoxicity, Mutagenicity, and Methemoglobin Formation In VitroIntraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivity.Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis.Probing the molecular mechanism of hypericin-induced parasite death provides insight into the role of spermidine beyond redox metabolism in Leishmania donovani.Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovaniUse of antimony in the treatment of leishmaniasis: current status and future directions.Genome evolution in trypanosomatid parasites.Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicansDistinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress.Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.Upregulation of Cysteine Synthase and Cystathionine β-Synthase Contributes to Leishmania braziliensis Survival under Oxidative Stress.Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40.Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect Macrophages
P2860
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P2860
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Redox control in trypanosomati ...... othione-based thiol metabolism
@ast
Redox control in trypanosomati ...... othione-based thiol metabolism
@en
Redox control in trypanosomati ...... othione-based thiol metabolism
@nl
type
label
Redox control in trypanosomati ...... othione-based thiol metabolism
@ast
Redox control in trypanosomati ...... othione-based thiol metabolism
@en
Redox control in trypanosomati ...... othione-based thiol metabolism
@nl
prefLabel
Redox control in trypanosomati ...... othione-based thiol metabolism
@ast
Redox control in trypanosomati ...... othione-based thiol metabolism
@en
Redox control in trypanosomati ...... othione-based thiol metabolism
@nl
P3181
P1476
Redox control in trypanosomati ...... othione-based thiol metabolism
@en
P2093
Marcelo A Comini
R Luise Krauth-Siegel
P304
P3181
P356
10.1016/J.BBAGEN.2008.03.006
P407
P577
2008-11-01T00:00:00Z