An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications
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Identification and characterization of a novel human aldose reductase-like geneMolecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binderMolecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductaseAldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugatesNAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzymeNovel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteinsRefined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestatEnzymes of the cyclooxygenase pathways of prostanoid biosynthesisCrystal structure of CHO reductase, a member of the aldo-keto reductase superfamilyStructure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds: alteration of pyridine nucleotide binding by a single amino acid substitutionThe crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamilyThe 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenaseStructure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductasesCrystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiaeStructural and biochemical analyses of YvgN and YtbE fromBacillus subtilisQuantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductaseCrystal Structure of Human Liver 4-3-Ketosteroid 5 -Reductase (AKR1D1) and Implications for Substrate Binding and CatalysisThe Role of Cys-298 in Aldose Reductase FunctionStructure of aldose reductase from Giardia lambliaStructures ofSaccharomyces cerevisiaeD-arabinose dehydrogenase Ara1 and its complex with NADPH: implications for cofactor-assisted substrate recognitionThree-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamilyStudies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complexCrystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolutionCalculating an optimal box size for ligand docking and virtual screening against experimental and predicted binding pocketsFunctional studies of aldo-keto reductases in Saccharomyces cerevisiaeStructural and kinetic modifications of aldose reductase by S-nitrosothiolsMolecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase familyRedox activation of aldose reductase in the ischemic heartAn ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductasesAFAP-120. A variant form of the Src SH2/SH3-binding partner AFAP-110 is detected in brain and contains a novel internal sequence which binds to a 67-kDa protein.The ups and downs of protein topology; rapid comparison of protein structure.Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis.Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms.A vertebrate aldo-keto reductase active with retinoids and ethanol.Cloning and expression of two novel aldo-keto reductases from Digitalis purpurea leaves.Structural and functional properties of a yeast xylitol dehydrogenase, a Zn2+-containing metalloenzyme similar to medium-chain sorbitol dehydrogenases.Cloning of a rat brain succinic semialdehyde reductase involved in the synthesis of the neuromodulator gamma-hydroxybutyrate.Structure based comprehensive modelling, spatial fingerprints mapping and ADME screening of curcumin analogues as novel ALR2 inhibitors.Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment.Biochemical characterization of a functional recombinant aryl-alcohol dehydrogenase from Taiwanofungus camphorata.
P2860
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P2860
An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
An unlikely sugar substrate si ...... ated in diabetic complications
@ast
An unlikely sugar substrate si ...... ated in diabetic complications
@en
An unlikely sugar substrate si ...... ated in diabetic complications
@nl
type
label
An unlikely sugar substrate si ...... ated in diabetic complications
@ast
An unlikely sugar substrate si ...... ated in diabetic complications
@en
An unlikely sugar substrate si ...... ated in diabetic complications
@nl
prefLabel
An unlikely sugar substrate si ...... ated in diabetic complications
@ast
An unlikely sugar substrate si ...... ated in diabetic complications
@en
An unlikely sugar substrate si ...... ated in diabetic complications
@nl
P2093
P356
P1433
P1476
An unlikely sugar substrate si ...... ated in diabetic complications
@en
P2093
D K Wilson
F A Quiocho
K H Gabbay
K M Bohren
P356
10.1126/SCIENCE.1621098
P407
P577
1992-07-03T00:00:00Z