HIV evolution in response to HLA-restricted CTL selection pressures: a population-based perspective
about
Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity.Epitope discovery with phylogenetic hidden Markov models.Detecting consistent patterns of directional adaptation using differential selection codon models.Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trialsExploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responsesFactors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial.High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection.Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes.Selection and accumulation of an HIV-1 escape mutant by three types of HIV-1-specific cytotoxic T lymphocytes recognizing wild-type and/or escape mutant epitopes.Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B.Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?Immunogenetics of HIV disease.Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progressionUnique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study.A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda.HLA and infectious diseases.Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection.Host genetic variation and HIV disease: from mapping to mechanism.Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins.Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.Selection pressure in CD8⁺ T-cell epitopes in the pol gene of HIV-1 infected individuals in Colombia. A bioinformatic approachWidespread impact of HLA restriction on immune control and escape pathways of HIV-1Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals.Cytotoxic T-lymphocyte escape mutations identified by HLA association favor those which escape and revert rapidly.HIV-1 drug resistance: where do polymorphisms fit in?HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation.Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico.Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control
P2860
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P2860
HIV evolution in response to HLA-restricted CTL selection pressures: a population-based perspective
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
HIV evolution in response to H ...... a population-based perspective
@ast
HIV evolution in response to H ...... a population-based perspective
@en
HIV evolution in response to H ...... a population-based perspective
@nl
type
label
HIV evolution in response to H ...... a population-based perspective
@ast
HIV evolution in response to H ...... a population-based perspective
@en
HIV evolution in response to H ...... a population-based perspective
@nl
prefLabel
HIV evolution in response to H ...... a population-based perspective
@ast
HIV evolution in response to H ...... a population-based perspective
@en
HIV evolution in response to H ...... a population-based perspective
@nl
P1476
HIV evolution in response to H ...... a population-based perspective
@en
P2093
Jonathan M Carlson
P304
P356
10.1016/J.MICINF.2008.01.013
P407
P577
2008-04-01T00:00:00Z