Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
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Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosomeHuman Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysisCullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cellsWD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligaseCUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligaseThe CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaSCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigenBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseThe SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitroStudying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box proteinTargeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesisThe F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissuesStructure and function of WD40 domain proteinsSCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signalingX-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionSLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNPDegradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complexHsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites.The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligationThe xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells.EVM005: an ectromelia-encoded protein with dual roles in NF-κB inhibition and virulenceIn vivo interference with Skp1 function leads to genetic instability and neoplastic transformationDDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligasesDictyostelium amoebae lacking an F-box protein form spores rather than stalk in chimeras with wild typeThe F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblastsSkp2 is a promising therapeutic target in breast cancer.Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Dysregulation of core components of SCF complex in poly-glutamine disordersUbiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsThe draft genome and transcriptome of Panagrellus redivivus are shaped by the harsh demands of a free-living lifestyleNoncatalytic requirement for cyclin A-cdk2 in p27 turnoverCUL1 promotes trophoblast cell invasion at the maternal-fetal interface.Connexin Controls Cell-Cycle Exit and Cell Differentiation by Directly Promoting Cytosolic Localization and Degradation of E3 Ligase Skp2.Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer.
P2860
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P2860
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@ast
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@en
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@nl
type
label
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@ast
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@en
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@nl
prefLabel
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@ast
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@en
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@nl
P1476
Human CUL-1, but not other cul ...... complex with SKP2 and cyclin A
@en
P2093
P304
P407
P577
1998-06-01T00:00:00Z