The human Mediator complex: a versatile, genome-wide regulator of transcription - Wikidata - awgldk - TriplyDB

The human Mediator complex: a versatile, genome-wide regulator of transcription

The human Mediator complex: a versatile, genome-wide regulator of transcription

http://www.wikidata.org/entity/Q28276700

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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex Human mediator subunit MED26 functions as a docking site for transcription elongation factors A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery Mediator and cohesin connect gene expression and chromatin architecture Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth Importance of Mediator complex in the regulation and integration of diverse signaling pathways in plants Mutual relationships between transcription and pre-mRNA processing in the synthesis of mRNA The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation Promoter clearance by RNA polymerase II Transcriptional regulation by coactivators in embryonic stem cells Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila Solution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25 Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response A cardiac microRNA governs systemic energy homeostasis by regulation of MED13 Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs Disordered proteinaceous machines Control of the embryonic stem cell state Selective inhibition of tumor oncogenes by disruption of super-enhancers A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.Tumor-suppressive effects of CDK8 in endometrial cancer cells.Inferring protein-protein interaction complexes from immunoprecipitation data Towards a Hierarchical Strategy to Explore Multi-Scale IP/MS Data for Protein Complexes.Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair.Adhesion GPCRs in Tumorigenesis.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling Mutation of MED12 is not a frequent occurrence in prostate cancer of Korean patients.Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila.Mediator and human disease Mediator subunit 12 is required for neutrophil development in zebrafish Transcriptional regulation and its misregulation in disease.The Kto-Skd complex can regulate ptc expression by interacting with Cubitus interruptus (Ci) in the Hedgehog signaling pathway.The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8.Functionally diverse dendritic mRNAs rapidly associate with ribosomes following a novel experience.MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.Mediator acts upstream of the transcriptional activator Gal4.

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The human Mediator complex: a versatile, genome-wide regulator of transcription

http://www.wikidata.org/entity/Q28276700

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The human Mediator complex: a versatile, genome-wide regulator of transcription

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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J.TIBS.2010.02.004

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Trends in Biochemical Sciences

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The human Mediator complex: a versatile, genome-wide regulator of transcription

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Dylan J Taatjes

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P2860

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1

A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

Composite co-activator ARC mediates chromatin-directed transcriptional activation

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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