TGF-β signaling, activated stromal fibroblasts, and cysteine cathepsins B and L drive the invasive growth of human melanoma cells
about
Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritisOver-expression of cathepsin B in hepatocellular carcinomas predicts poor prognosis of HCC patientsRegulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.BRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity.Pericellular proteolysis in cancerCofilin drives cell-invasive and metastatic responses to TGF-β in prostate cancer.Expression of molecular factors correlated with metastasis in small cell lung cancer and their significance.Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cellsInsights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma.Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis.Activity levels of cathepsins B and L in tumor cells are a biomarker for efficacy of reovirus-mediated tumor cell killing.A clinicopathological analysis of primary mucosal malignant melanoma.Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells.UV radiation promotes melanoma dissemination mediated by the sequential reaction axis of cathepsins-TGF-β1-FAP-α.Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts.Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness.Cathepsin Protease Inhibition Reduces Endometriosis Lesion Establishment.TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.
P2860
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P2860
TGF-β signaling, activated stromal fibroblasts, and cysteine cathepsins B and L drive the invasive growth of human melanoma cells
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
TGF-β signaling, activated str ...... growth of human melanoma cells
@ast
TGF-β signaling, activated str ...... growth of human melanoma cells
@en
TGF-β signaling, activated str ...... growth of human melanoma cells
@nl
type
label
TGF-β signaling, activated str ...... growth of human melanoma cells
@ast
TGF-β signaling, activated str ...... growth of human melanoma cells
@en
TGF-β signaling, activated str ...... growth of human melanoma cells
@nl
prefLabel
TGF-β signaling, activated str ...... growth of human melanoma cells
@ast
TGF-β signaling, activated str ...... growth of human melanoma cells
@en
TGF-β signaling, activated str ...... growth of human melanoma cells
@nl
P2093
P1476
TGF-β signaling, activated str ...... growth of human melanoma cells
@en
P2093
Erkki Hölttä
Johanna Soikkeli
Olli Saksela
Susanna Virolainen
Tiina Jahkola
P304
P356
10.1016/J.AJPATH.2012.08.027
P407
P577
2012-12-01T00:00:00Z