The expression of isotope effects on enzyme-catalyzed reactions
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Binding isotope effects: boon and baneNeighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †Structure and reaction mechanism of human nicotinamide phosphoribosyltransferaseEnzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimesUse of isotope effects to elucidate enzyme mechanismsDemonstration of proton-coupled electron transfer in the copper-containing nitrite reductases.Importance of protein dynamics during enzymatic C-H bond cleavage catalysis.Synthesis of 11-thialinoleic acid and 14-thialinoleic acid, inhibitors of soybean and human lipoxygenasesEvidence of substantial carbon isotope fractionation among substrate, inorganic carbon, and biomass during aerobic mineralization of 1, 2-dichloroethane by Xanthobacter autotrophicus.Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosisCommon enzymological experiments allow free energy profile determination.On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosisDeuterium isotope effect on the metabolism of N-nitrosodimethylamine and related compounds by cytochrome P4502E1.Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme.Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactionsInvestigating the roles of putative active site residues in the oxalate decarboxylase from Bacillus subtilis.Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.Binding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparumA method to determine 18 O kinetic isotope effects in the hydrolysis of nucleotide triphosphates.Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2)A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.Enzymatic transition state theory and transition state analogue design.The isotope array, a new tool that employs substrate-mediated labeling of rRNA for determination of microbial community structure and function.Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.Field applicability of Compound-Specific Isotope Analysis (CSIA) for characterization and quantification of in situ contaminant degradation in aquifers.Influence of mass transfer on stable isotope fractionation.Mechanistic insights into F420-dependent glucose-6-phosphate dehydrogenase using isotope effects and substrate inhibition studies.Uridine phosphorylase from Trypanosoma cruzi: kinetic and chemical mechanisms.Determination of toxic pathways of metabolism by deuterium substitution.Carbon Isotope Fractionation during Catabolism and Anabolism in Acetogenic Bacteria Growing on Different Substrates.Isotope effect studies on the cytochrome P450 enzymes.Transition State Structure and Inhibition of Rv0091, a 5'-Deoxyadenosine/5'-methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase.Kinetic competence of the cADP-ribose-CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling.Transition state analysis of thymidine hydrolysis by human thymidine phosphorylase.Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin.Transition-state structure of neisseria meningitides 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.Brønsted analysis of aspartate aminotransferase via exogenous catalysis of reactions of an inactive mutant.Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: tunneling in the substrate backbone as well as the transferred hydrogen.
P2860
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P2860
The expression of isotope effects on enzyme-catalyzed reactions
description
1981 nî lūn-bûn
@nan
1981 թուականին հրատարակուած գիտական յօդուած
@hyw
1981 թվականին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
The expression of isotope effects on enzyme-catalyzed reactions
@ast
The expression of isotope effects on enzyme-catalyzed reactions
@en
The expression of isotope effects on enzyme-catalyzed reactions
@nl
type
label
The expression of isotope effects on enzyme-catalyzed reactions
@ast
The expression of isotope effects on enzyme-catalyzed reactions
@en
The expression of isotope effects on enzyme-catalyzed reactions
@nl
prefLabel
The expression of isotope effects on enzyme-catalyzed reactions
@ast
The expression of isotope effects on enzyme-catalyzed reactions
@en
The expression of isotope effects on enzyme-catalyzed reactions
@nl
P1476
The expression of isotope effects on enzyme-catalyzed reactions
@en
P2093
D B Northrop
P304
P356
10.1146/ANNUREV.BI.50.070181.000535
P407
P577
1981-01-01T00:00:00Z