The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase
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Endoreplication: polyploidy with purposeCyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidizationc-Fos/activator protein-1 transactivates wee1 kinase at G(1)/S to inhibit premature mitosis in antigen-specific Th1 cells.APC/C--the master controller of origin licensing?Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting propertyNew roles for cyclin E in megakaryocytic polyploidization.The incredible journey: From megakaryocyte development to platelet formation.Megakaryocytes and beyond: the birth of platelets.Stem cell pluripotency: a cellular trait that depends on transcription factors, chromatin state and a checkpoint deficient cell cycle.Hepatocytes polyploidization and cell cycle control in liver physiopathology.Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells.Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinaseA role for cyclin D3 in the endomitotic cell cycleReprogramming the cell cycle for endoreduplication in rodent trophoblast cells.Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.Wnt signaling through the Ror receptor in the nervous system.Heterologous expression of the transcriptional regulator escargot inhibits megakaryocytic endomitosis.Progress in bio-manufacture of platelets for transfusion.The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity.Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes.Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosisThrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis.Overexpression of nuclear distribution protein (hNUDC) causes pro-apoptosis and differentiation in Dami megakaryocytes.Octaploid Meth-A cells are established from a highly polyploidized cell population.Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization.Eternal youth, the fate of developing Arabidopsis leaves upon Rhodococcus fascians infection.Polyploidy road to therapy-induced cellular senescence and escape.
P2860
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P2860
The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@ast
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@en
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@nl
type
label
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@ast
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@en
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@nl
prefLabel
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@ast
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@en
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@nl
P2860
P356
P1476
The cell cycle in polyploid me ...... yclin B1-dependent cdc2 kinase
@en
P2860
P304
P356
10.1074/JBC.271.8.4266
P407
P50
P577
1996-02-23T00:00:00Z