The arrangement of intra- and intermolecular disulfide bonds in the carboxyterminal, non-collagenous aggregation and cross-linking domain of basement-membrane type IV collagen
about
The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-linkMolecular cloning of the human Goodpasture antigen demonstrates it to be the alpha 3 chain of type IV collagenA sulfilimine bond identified in collagen IVIdentification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activityCrystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranesMammalian collagen IVThe alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links.Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo.Severe alport phenotype in a woman with two missense mutations in the same COL4A5 gene and preponderant inactivation of the X chromosome carrying the normal allele.Basement membrane proteins: structure, assembly, and cellular interactions.Mutation in the alpha 5(IV) collagen chain in juvenile-onset Alport syndrome without hearing loss or ocular lesions: detection by denaturing gradient gel electrophoresis of a PCR product.A switch in disulfide linkage during minicollagen assembly in Hydra nematocystsRenal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiationTransfer of the alpha 5(IV) collagen chain gene to smooth muscle restores in vivo expression of the alpha 6(IV) collagen chain in a canine model of Alport syndromeEndothelial cells use alpha 2 beta 1 integrin as a laminin receptor.Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes.A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes.COL4A3/COL4A4 mutations and features in individuals with autosomal recessive Alport syndrome.Molecular properties of the Goodpasture epitope.Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies.The biochemistry of cancer dissemination.Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis.Impact of heparan sulfate chains and sulfur-mediated bonds on the mechanical properties of bovine lens capsule.Increased Goodpasture antigen-binding protein expression induces type IV collagen disorganization and deposit of immunoglobulin A in glomerular basement membrane.Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the alpha1alpha1alpha2 collagen IV network: a role for the post-translational modification of lysine 211 to hydroxylysine 211 in hexamer asThe NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist?Recombinant alpha-chains of type IV collagen demonstrate that the amino terminal of the Goodpasture autoantigen is crucial for antibody recognition.The recognition sites of the integrins alpha1beta1 and alpha2beta1 within collagen IV are protected against gelatinase A attack in the native protein.
P2860
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P2860
The arrangement of intra- and intermolecular disulfide bonds in the carboxyterminal, non-collagenous aggregation and cross-linking domain of basement-membrane type IV collagen
description
1988 nî lūn-bûn
@nan
1988 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
name
The arrangement of intra- and ...... ment-membrane type IV collagen
@ast
The arrangement of intra- and ...... ment-membrane type IV collagen
@en
The arrangement of intra- and ...... ment-membrane type IV collagen
@nl
type
label
The arrangement of intra- and ...... ment-membrane type IV collagen
@ast
The arrangement of intra- and ...... ment-membrane type IV collagen
@en
The arrangement of intra- and ...... ment-membrane type IV collagen
@nl
prefLabel
The arrangement of intra- and ...... ment-membrane type IV collagen
@ast
The arrangement of intra- and ...... ment-membrane type IV collagen
@en
The arrangement of intra- and ...... ment-membrane type IV collagen
@nl
P2093
P2860
P1433
P1476
The arrangement of intra- and ...... ment-membrane type IV collagen
@en
P2093
P2860
P304
P356
10.1111/J.1432-1033.1988.TB14321.X
P407
P577
1988-10-01T00:00:00Z