ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics
about
Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoniInhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to PraziquantelModulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel.Anthelmintics are substrates and activators of nematode P glycoprotein.Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantelGene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones.PGP expression in Cooperia oncophora before and after ivermectin selection.Moxidectin and the avermectins: Consanguinity but not identity.Schistosome ABC multidrug transporters: From pharmacology to physiology.Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.Pharmacology and potential physiological significance of schistosome multidrug resistance transportersUnique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistanceDrug-transporter mediated interactions between anthelminthic and antiretroviral drugs across the Caco-2 cell monolayers.Characterisation of P-glycoprotein-9.1 in Haemonchus contortus.ABC multidrug transporters in schistosomes and other parasitic flatwormsSchistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibilityMolecular cloning and characterization of a P-glycoprotein from the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae).P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance.Triclabendazole progress report, 2005-2009: an advancement of learning?Overcoming drug resistance for macro parasites.Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae.Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus.ABC-B transporter genes in Dirofilaria immitis.Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.Erratum to: inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.ABC transporters as a multidrug detoxification mechanism in Rhipicephalus (Boophilus) microplus.Increased susceptibility of a triclabendazole (TCBZ)-resistant isolate of Fasciola hepatica to TCBZ following co-incubation in vitro with the P-glycoprotein inhibitor, R(+)-verapamil.Ameliorative effect of vitamin C against hepatotoxicity induced by emamectin benzoate in rats.
P2860
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P2860
ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@ast
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@en
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@nl
type
label
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@ast
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@en
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@nl
prefLabel
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@ast
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@en
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@nl
P2093
P3181
P356
P1476
ABC transporter modulation: a ...... rocyclic lactone anthelmintics
@en
P2093
Anne Lespine
Michel Alvinerie
Peter Geldhof
Roger K Prichard
P3181
P356
10.1016/J.PT.2008.03.011
P407
P577
2008-07-01T00:00:00Z