Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression
about
Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentMetabolomics in rheumatic diseases: desperately seeking biomarkersKey Players in Choline Metabolic Reprograming in Triple-Negative Breast CancerDownregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer CellsMetformin Decouples Phospholipid Metabolism in Breast Cancer CellsFunctional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferationPhospholipase D1 and choline kinase-α are interactive targets in breast cancer.Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft modelsActivation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA.Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy.A critical role for choline kinase-alpha in the aggressiveness of bladder carcinomasGlycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancerPrognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy.Choline kinase alpha and hexokinase-2 protein expression in hepatocellular carcinoma: association with survival.Clinical characteristics and biomarkers of breast cancer associated with choline concentration measured by 1H MRS.17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2A novel small molecule antagonist of choline kinase-α that simultaneously suppresses MAPK and PI3K/AKT signalingCholine metabolism in malignant transformation.Characterization of human bladder cell membrane during cancer transformation.Choline kinase inhibition in rheumatoid arthritis.Magnetic resonance spectroscopy for detection of choline kinase inhibition in the treatment of brain tumorsIn vivo proton MR spectroscopy of pancreatic neuroendocrine tumors in a multiple endocrine neoplasia type 1 conditional knockout mouse modelCholine kinase alpha-Putting the ChoK-hold on tumor metabolism.Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition.PET Tracers for Clinical Imaging of Breast Cancer.Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism.Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer.Magnetic Resonance Spectroscopy of siRNA-Based Cancer TherapyPharmacodynamic markers for choline kinase down-regulation in breast cancer cells.Characterization of choline kinase in human endothelial cells.A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells.Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopyOverexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.MR evaluation of response to targeted treatment in cancer cells.Approaches for the study of cancer: towards the integration of genomics, proteomics and metabolomics.The role of phosphatidylcholine and choline metabolites to cell proliferation and survival.
P2860
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P2860
Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Choline kinase activation is a ...... s and breast tumor progression
@ast
Choline kinase activation is a ...... s and breast tumor progression
@en
Choline kinase activation is a ...... s and breast tumor progression
@nl
type
label
Choline kinase activation is a ...... s and breast tumor progression
@ast
Choline kinase activation is a ...... s and breast tumor progression
@en
Choline kinase activation is a ...... s and breast tumor progression
@nl
prefLabel
Choline kinase activation is a ...... s and breast tumor progression
@ast
Choline kinase activation is a ...... s and breast tumor progression
@en
Choline kinase activation is a ...... s and breast tumor progression
@nl
P2093
P3181
P1433
P1476
Choline kinase activation is a ...... s and breast tumor progression
@en
P2093
Agustín Rodríguez-González
Ana Ramírez de Molina
David Olmeda
Diego Megías
Juan Carlos Lacal
Mónica Báñez-Coronel
Ruth Gutiérrez
P304
P3181
P356
10.1158/0008-5472.CAN-04-0489
P407
P577
2004-09-15T00:00:00Z