betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
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Stabilizing versus destabilizing the microtubules: a double-edge sword for an effective cancer treatment option?Microtubule-binding agents: a dynamic field of cancer therapeutics.High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancerClass III β-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancerβIII-Tubulin: biomarker of taxane resistance or drug target?Specific β-tubulin isotypes can functionally enhance or diminish epothilone B sensitivity in non-small cell lung cancer cellsMicrotubules and their role in cellular stress in cancerMovers and shakers: cell cytoskeleton in cancer metastasis.Peloruside- and laulimalide-resistant human ovarian carcinoma cells have βI-tubulin mutations and altered expression of βII- and βIII-tubulin isotypes.βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancerTherapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer.Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer.Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells.Slug increases sensitivity to tubulin-binding agents via the downregulation of βIII and βIVa-tubulin in lung cancer cells.Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel2-(m-Azidobenzoyl)taxol binds differentially to distinct β-tubulin isotypesRecent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer.βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells.Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin.Hypoxia-inducible factor-2α (HIF-2α), but not HIF-1α, is essential for hypoxic induction of class III β-tubulin expression in human glioblastoma cells.RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model.Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue.An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy ResistancePrognostic effect of class III β-tubulin and Topoisomerase-II in patients with advanced thymic carcinoma who received combination chemotherapy, including taxanes or topoisomerase-II inhibitors.βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel.Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration.Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway.Gene expression analysis of SCC tumor cells in muscle tissue.[Down-regulated βIII-tubulin expression can reverse paclitaxel resistance in A549/taxol cells lines].
P2860
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P2860
betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@ast
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@en
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@nl
type
label
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@ast
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@en
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@nl
prefLabel
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@ast
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@en
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@nl
P2093
P1433
P1476
betaIII-tubulin is a multifunc ...... in non-small cell lung cancer
@en
P2093
Joshua A McCarroll
Maria Kavallaris
Marjorie Liu
Pei Pei Gan
P304
P356
10.1158/0008-5472.CAN-09-4487
P407
P577
2010-06-15T00:00:00Z